Protein Alignment CG10516 and FBXO45

DIOPT Version :9

• Sequence 1: NP_648819.2
• Gene: CG10516 / 39738
• FlyBaseID: FBgn0036549
• Length: 342
• Species: Drosophila melanogaster
• Sequence 2: NP_001099043.1
• Gene: FBXO45 / 200933
• HGNCID: 29148
• Length: 286
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 53/223 - (23%)
• Similarity: 81/223 - (36%)
• Gaps: 56/223 - (25%)

  Fly    37 RCQCGEDESGNVNAWRWHATDESDAVVTDRDIIFH-PTY----------------SQGTAIVRGE 84
            ||..|::   |...||..............||:.: |:|                |:...|.:..
Human    68 RCLHGDE---NSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRNVYIKKNG 129

  Fly    85 QALKTNMV-----------------HFWEMRVITTLAGTDVMFGIGTESVNL---GQFKFHFVSA 129
            ..|..|.:                 |.||:.....| ||..:.||.|:...:   |     :|:.
Human   130 FTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEGPL-GTVAVIGIATKRAPMQCQG-----YVAL 188

  Fly   130 LGTNAQSWGFS-YSGRIQHCGEL---LPY---GQKFSQGCLIGVCLDRTRGHLEFYLNRRSLGVA 187
            ||::.||||:: ....:.|.||:   .|.   ..|:..|..|.|.||.....|.|......||||
Human   189 LGSDDQSWGWNLVDNNLLHNGEVNGSFPQCNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVA 253

  Fly   188 YTNVPTDPDVKIYPMVCSTAAKSVIRLI 215
            :..:   |.|.:||.|.:....:.:.|:
Human   254 FRGL---PKVCLYPAVSAVYGNTEVTLV 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10516	NP_648819.2	SPRY_SOCS3	51..233	CDD:293936	49/209 (23%)
FBXO45	NP_001099043.1	F-box-like	38..83	CDD:372399	6/17 (35%)
		SPRY_Fbox	112..286	CDD:293964	43/176 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810