Protein Alignment Brr2 and AT5G61140

DIOPT Version :10

• Sequence 1: NP_648818.3
• Gene: Brr2 / 39737
• FlyBaseID: FBgn0263599
• Length: 2142
• Species: Drosophila melanogaster
• Sequence 2: NP_001190584.1
• Gene: AT5G61140 / 836235
• AraportID: AT5G61140
• Length: 2157
• Species: Arabidopsis thaliana
• Alignment Length: 2181
• Identity: 861/2181 - (39%)
• Similarity: 1285/2181 - (58%)
• Gaps: 201/2181 - (9%)

  Fly    64 TEERKVKRQK-----------------RDEAQYDFERMKGATLL-------SEG--IDE---MVG 99
            |||:..||.|                 |:....|...::..|:|       |.|  :||   ...
plant    57 TEEKNPKRHKYRDFVMLVQLPRLTSSLREPFDIDQAYLRRKTILQTLNKPRSSGNRLDESDLAKR 121

  Fly   100 IVYR--PKTQETRQTYEVLLSFIQEAL-----GDQPRDILCGA-------ADEILAVLKNDRLKD 150
            ||::  ..:.|.||.|:..:..:.|.:     .|:.|::...|       .:|..:.: ||.:..
plant   122 IVHQWEGASLEVRQAYKQFIGAVVELIDREVPSDEFREVAFSAYRLFNNPVEEDDSDI-NDNISI 185

  Fly   151 RERKKDIDSLLG-AVTD----------------------ERFALLVNLGKKITDFGSDAVNALTA 192
            ..:|.::.:|:| ||:|                      |.:|..||.|   .:||:|.|..|.|
plant   186 SGKKLELQNLVGHAVSDANVKNVASFAQALYSIQPTHQSETYADEVNGG---AEFGADLVFNLPA 247

  Fly   193 APNNEEQIDETYGINVQFEESEEESDNDMYGEIRDDDAQDEGEEARIDHTLHAENLAN-EEAANN 256
            ....|..:|||..::|:                 .:||          ||..:|..:. .:..||
plant   248 RFLVEASLDETGFVDVE-----------------SNDA----------HTSFSEGWSGVSDTKNN 285

  Fly   257 VKKERSLHPLDIDAYWLQRCLSKFYKDAMVSQSK---AADVLKILKDAADDRDCENQLVLLLGYD 318
            :...:      .:..||:....:..::.....|:   |..:.:.|.......:....|:.|:|..
plant   286 LSAGK------FNLSWLRDACGRMVRETNSQLSREELAMAICRFLDSDKPGEEIAGDLLDLVGDG 344

  Fly   319 CFDFIKQLKLNR----------QMVLYCTMLAS--------------AQTDSERQRIREKMRGNS 359
            .|:.::.|.::|          ||:|.....||              .||:|.:|  .||:|
plant   345 AFETVQDLIMHRKEIVDAIHHGQMILKSDKAASNTQSRMPTYGTQVTVQTESAKQ--IEKLR--- 404

  Fly   360 ALAKILRQLDTGKSEDQEEGEARGSKRGKGDAEDGGAAAAGQVAGVRQLLELEE--MAFTQ--GS 420
                           .:||      |:.|.:| |.|..:....|....|||..|  .||..  ||
plant   405 ---------------RKEE------KKNKRNA-DLGLESEISEANFSSLLEASEKKTAFEDLIGS 447

  Fly   421 HFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEGFKTLNRIQ 485
            ....:....||.|:.||..||||||.:|..........|:|..:.:|..:.|..|.|:|:|||||
plant   448 GEANSLALALPQGTVRKHLKGYEEVFIPPTPTAQMKPGEKLIEIKELDDFAQAAFHGYKSLNRIQ 512

  Fly   486 SRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQE 550
            ||:::....::||:|:||||||||||:|:::::.||.:|. .||.::..:|||:||||||:|..|
plant   513 SRIFQTVYHTNENILVCAPTGAGKTNIAMISVLHEIKQHF-RDGYLHKNEFKIVYVAPMKALAAE 576

  Fly   551 MVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIID 615
            :...|.||||..|:.|.|||||.|||:.::..||:||.||||||:||||..:.:...||:|:|||
plant   577 VTSAFSRRLAPLNMVVKELTGDMQLTKTELEETQMIVTTPEKWDVITRKSSDMSMSMLVKLLIID 641

  Fly   616 EIHLLHDERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSY 680
            |:|||:|:||.|:|||||||:|.:|:||..:|:||||||||:|..||.||||..|.||||||:||
plant   642 EVHLLNDDRGAVIEALVARTLRQVESTQTMIRIVGLSATLPSYLQVAQFLRVNTDTGLFYFDSSY 706

  Fly   681 RPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGR-NQVLVFVHSRKETGKTARAVRDMCLE 744
            |||.|.|||||:||.....|.:::|||.|:|.::...: :|.::||||||:|.|||..:.|:..:
plant   707 RPVPLAQQYIGITEHNFAARNELLNEICYKKVVDSIKQGHQAMIFVHSRKDTSKTAEKLVDLARQ 771

  Fly   745 QDTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVL 809
            .:||..|..|.....::::.:..:.:|.:|.:....||.||||||.|.||||.|.||:|..::||
plant   772 YETLDLFTNETHPQFQLMKKDVMKSRNKDLVKFFEAGFGIHHAGMLRSDRTLTERLFSDGLLKVL 836

  Fly   810 VSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHS 874
            |.|||||||||||||||:|||||:|:.:.|.|.:|..|||:|:.|||||||:|..||||:||:|.
plant   837 VCTATLAWGVNLPAHTVVIKGTQLYDAKAGGWKDLGMLDVMQIFGRAGRPQFDKSGEGIIITSHD 901

  Fly   875 ELQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVS 939
            :|.:||.||..||||||||||.|.|.||||:|||||.::::|..|||||||.|||..||..||:.
plant   902 KLAYYLRLLTSQLPIESQFISSLKDNLNAEVVLGTVTNVKEACAWLGYTYLSIRMKLNPLAYGIG 966

  Fly   940 HDAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQL 1004
            .:.|.|||.|...:..|:..||..|:::.::::|.|:|:|..|:|||:|||:|:.:.::.|||::
plant   967 WEEIIADPSLSLKQRALVADAARSLDKAKMMRFDEKSGNFYCTELGRVASHFYIQYSSVETYNEM 1031

  Fly  1005 LKQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMER-VPIPIKESIEEHSAKVNVLLQAYIS 1068
            ||:.::|.|:..:.:.||||.:|.|||||:.||:.|... .|:.:|........|:::|:|.|||
plant  1032 LKRHMNESEIINMVAHSSEFENIVVREEEQHELETLARSCCPLEVKGGPSNKHGKISILIQLYIS 1096

  Fly  1069 QLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFK 1133
            :..::.|:|:||..:|:.|.||:|||:|||.|.:||.::....|..||.:||::|....|||||:
plant  1097 RGSIDAFSLVSDASYISASLARIMRALFEICLRKGWCEMTLFMLEYCKAVDRQLWPHQHPLRQFE 1161

  Fly  1134 K-MPDEIAKKLEKKHFPWGRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGT 1197
            : :|.:|.:|||::......||::|..|:|.|||....|:.:.:.:..||.::|:..:.||||..
plant  1162 RDLPSDILRKLEERRDDLDHLYEMEEKEIGALIRYNPGGRLVKQHLGYFPSIQLAATVSPITRTV 1226

  Fly  1198 LRVELTITPDFQWDEKVHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQ-LKFFVPVFEP 1261
            |:|:|.|||:|.|.::.||.:..:|:||||.:::.|.|.:.|.|.::.::.|.| |.|.||:|||
plant  1227 LKVDLLITPNFIWKDRFHGTALRWWILIEDTENDYIYHSDLFTLTKRMARGEPQKLSFTVPIFEP 1291

  Fly  1262 LPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFP 1326
            .||||::..|||.|:.|||...:||.:|.|||.....||||||:|||:::|....:||.|  :|.
plant  1292 HPPQYYVHAVSDSWLHAETYFTISFHNLALPEARTSHTELLDLKPLPVTSLGNKLYESLY--KFS 1354

  Fly  1327 QFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFA 1391
            .|||||||:|:.:|::|.||.|||||||||...||.|::|||:||.|.:.||:...:|:......
plant  1355 HFNPIQTQIFHVLYHTDNNVLVGAPTGSGKTISAELAMLRLFSTQPDMKVVYIAPLKAIVRERMN 1419

  Fly  1392 DWHSKF-GSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDEL 1455
            ||.... ..|..::|::||:...||..:....::|:|.:|||.:||.|..|..|:.|.|.|:||:
plant  1420 DWKKHLVAPLGKEMVEMTGDYTPDLVALLSADIIISTPEKWDGISRNWHTRSYVKKVGLVILDEI 1484

  Fly  1456 QLVGGEEGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPI 1520
            .|:|.:.||:||::.|||||||||.|:.:|.|.||.:|.:|.|:|.|||......|||.|||||:
plant  1485 HLLGADRGPILEVIVSRMRYISSQTERSVRFVGLSTALANAGDLADWLGVGEIGLFNFKPSVRPV 1549

  Fly  1521 PLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHKPVIVFVSSRKQARLTAIDVLTYAASDLQP 1585
            |:|:|||||...:...|:.:|:||.|.||..:|..|||::|||||:|.||||:|::.:||||..|
plant  1550 PIEVHIQGYPGKYYCPRMNSMNKPAYAAICTHSPTKPVLIFVSSRRQTRLTALDLIQFAASDEHP 1614

  Fly  1586 NRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLC 1650
            .:|....|||::..|.::||:.|:.||..|:...|.||:..|...||:||.:..:||.|.:..|.
plant  1615 RQFLSVSEEDLQMVLSQITDQNLRHTLQFGIGLHHAGLNDHDRSAVEELFTNNKIQVLVSTSTLA 1679

  Fly  1651 WGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKK 1715
            ||:::.||||||..|::::||...|.|:|:|::|||:|||.||..|...|.|::....||.|:||
plant  1680 WGVNLPAHLVIIKGTEYFDGKTKRYVDFPLTEILQMMGRAGRPQFDQHGKAVILVHEPKKSFYKK 1744

  Fly  1716 FINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHL 1780
            |:.||.|:||.|..::|||||||:|:.||.||:|||.|||||:|:|||..||.||.|:|.....:
plant  1745 FLYEPFPVESSLKEKLHDHFNAEIVSGTIGNKEDAVHYLTWTYLFRRLMANPAYYGLEGTQDETI 1809

  Fly  1781 SDHLSELVENTLSDLEQSKCISVEDDMDTLPLNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLL 1845
            ..:||.||:.|..|||.|.|:.|.:| ...|..||.||:.||:.|.|:.:|..::...|.:...|
plant  1810 CSYLSRLVQTTFEDLEDSGCLKVNED-SVEPTMLGTIASQYYLCYMTVSMFGSNIGPDTSLEAFL 1873

  Fly  1846 EIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQLG- 1909
            .|::.|:||:::.|||:||...:|||.|:...:...:     .:|||:|.|||.|||.|:|.|.
plant  1874 HILAGASEYDELPVRHNEENYNKTLSDRVRYPVDNNH-----LDDPHVKANLLFQAHFSQLALPI 1933

  Fly  1910 PELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWS-KDSYLKQLPHFSPE 1973
            .:...|.:.:|.::||::||.:|:.:::||||.::..|.|.|||.|.||| :||.|..:|..:..
plant  1934 SDYNTDLKSVLDQSIRILQAMIDICANSGWLSSSLTCMRLLQMVMQGMWSDQDSSLWMIPCMNDL 1998

  Fly  1974 IVKRCTEKKIETVFDIMEL---------EDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVD 2029
            ::...|.:.|.|:..::.|         |:...:||.|  |||         |:|.|::|..:..
plant  1999 LLGSLTARGIHTLHQLLNLPRETLQSVTENFPASRLSQ--DLQ---------RFPRIQMNVRLQK 2052

  Fly  2030 KDRINSGSTVNVVVQLEREDE-VTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTLQQKAK 2093
            ||.........:.::||:..: .:...:||.||:.::|.||:|:||..|:.|.::||::...:..
plant  2053 KDSDGKKKPSTLEIRLEKTSKRNSSRALAPRFPKVKDEAWWLVLGDTSTSELFAVKRVSFTGRLI 2117

  Fly  2094 VKLDFVAPSPGKHDYTLYYMSDSYLGCDQEYKFSIE 2129
            .:::.........|..|..:||.|||.:||:  |||
plant  2118 TRMELPPNITSFQDTKLILVSDCYLGFEQEH--SIE 2151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brr2	NP_648818.3	Helicase_PWI	259..368	CDD:436309	23/135 (17%)
		DEXHc_Brr2_1	464..677	CDD:350777	117/212 (55%)
		BRR2	476..1020	CDD:440817	285/544 (52%)
		Sec63	982..1285	CDD:460740	124/305 (41%)
		BRR2	1309..1848	CDD:440817	245/539 (45%)
		DEXHc_Brr2_2	1325..1514	CDD:350779	86/189 (46%)
		Sec63	1811..2127	CDD:460740	104/327 (32%)
AT5G61140	NP_001190584.1	BRR2	490..1046	CDD:440817	288/556 (52%)
		DEXHc_ASCC3_1	507..703	CDD:350778	112/196 (57%)
		Sec63	1008..1315	CDD:460740	124/306 (41%)
		DEXHc_ASCC3_2	1355..1543	CDD:350780	85/187 (45%)
		BRR2	1356..1877	CDD:440817	241/521 (46%)
		Sec63	1839..2151	CDD:460740	105/329 (32%)