Protein Alignment Brr2 and AT2G42270

DIOPT Version :10

• Sequence 1: NP_648818.3
• Gene: Brr2 / 39737
• FlyBaseID: FBgn0263599
• Length: 2142
• Species: Drosophila melanogaster
• Sequence 2: NP_181756.1
• Gene: AT2G42270 / 818828
• AraportID: AT2G42270
• Length: 2172
• Species: Arabidopsis thaliana
• Alignment Length: 2187
• Identity: 1185/2187 - (54%)
• Similarity: 1587/2187 - (72%)
• Gaps: 72/2187 - (3%)

  Fly     2 ADAAARQLQYEYKANSNLVLQADVRLIERPRRD--EATGEVCSLVGKLDGTRMGDRYQRTKPEKT 64
            |:..||..||.||.||:|||.:|.|     |||  |::||..||.|::|....|||..|.:|.:.
plant     9 AEEQARLKQYGYKVNSSLVLNSDER-----RRDTHESSGEPESLRGRIDPKSFGDRVVRGRPHEL 68

  Fly    65 EERKVKRQKRDEAQYDF--------ERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVLLSFIQ 121
            :||..|.:|:.|...|.        .|::..::|::..|.    ||:|||:|||..:|::|..||
plant    69 DERLNKSKKKKERCDDLVSARESKRVRLREVSVLNDTEDG----VYQPKTKETRVAFEIMLGLIQ 129

  Fly   122 EALGDQPRDILCGAADEILAVLKNDRLKDRERKKDIDSLLGAVTDERFALLVNLGKKITDF--GS 184
            :.||.||.||:|||||||||||||:.:|:.|:|.:|:.||..:||:.|:..|::||.|||:  |.
plant   130 QQLGGQPLDIVCGAADEILAVLKNESVKNHEKKVEIEKLLNVITDQVFSQFVSIGKLITDYEEGG 194

  Fly   185 DAVNALTAAPNNEEQIDETYGINVQFEESEEESDNDMYGEIRDDDAQDEGEEARIDHT--LHAEN 247
            |   :|:...:.:..:|...|:.::.||.::|||.||..:.:|::.:|..|   ::.|  :....
plant   195 D---SLSGKASEDGGLDYDIGVALECEEDDDESDLDMVQDEKDEEDEDVVE---LNKTGVVQVGV 253

  Fly   248 LANEEAANNVKKERSLHPLDIDAYWLQRCLSKFYK---DAMVSQSKAADVLKILKDAADDRDCEN 309
            ..|.|.|...|::.||:.||||||||||.:|:.|:   ||...|..|.::||||.: .:|||.|.
plant   254 AINGEDARQAKEDTSLNVLDIDAYWLQRKISQEYEQKIDAQECQELAEELLKILAE-GNDRDVEI 317

  Fly   310 QLVLLLGYDCFDFIKQLKLNRQMVLYCTMLASAQTDSERQRIREKMRG-NSALAKILRQLDTGKS 373
            :|:..|.::.|..:|.|..||..|::||.||..:...||.:|.|:|.| .|.||.|:::|...::
plant   318 KLLEHLQFEKFSLVKFLLQNRLKVVWCTRLARGRDQEERNQIEEEMLGLGSELAAIVKELHAKRA 382

  Fly   374 EDQEEGEAR------------------GSKRGKGDAEDGGAAAAGQVAGVRQLLELEEMAFTQGS 420
            ..:|..|.|                  ...||..|.:|.. ...|.:.|.||:::||.:||.||.
plant   383 TAKEREEKREKDIKEEAQHLMDDDSGVDGDRGMRDVDDLD-LENGWLKGQRQVMDLESLAFNQGG 446

  Fly   421 HFMANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEGFKTLNRIQ 485
            ....|.:|:|||.|:|.:.|.::|||||.:.. .||:||:|..:..||::.||.|.|.:.|||:|
plant   447 FTRENNKCELPDRSFRIRGKEFDEVHVPWVSK-KFDSNEKLVKISDLPEWAQPAFRGMQQLNRVQ 510

  Fly   486 SRLYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQE 550
            |::|..||...:|:||||||||||||||:||::.::|.::|..||.|..::||:||||||:||.|
plant   511 SKVYGTALFKADNILLCAPTGAGKTNVAVLTILHQLGLNMNPGGTFNHGNYKIVYVAPMKALVAE 575

  Fly   551 MVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIID 615
            :|.:..:||..:.:||.||:||..||.::|..||:||.|||||||||||.|:||:..||||:|||
plant   576 VVDSLSQRLKDFGVTVKELSGDQSLTGQEIKETQIIVTTPEKWDIITRKSGDRTYTQLVRLLIID 640

  Fly   616 EIHLLHDERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSY 680
            |||||.|.||||||::||||:|.||:|:|.:|||||||||||..|||:||||....|||.||.||
plant   641 EIHLLDDNRGPVLESIVARTLRQIESTKEHIRLVGLSATLPNCDDVASFLRVDLKNGLFIFDRSY 705

  Fly   681 RPVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGRNQVLVFVHSRKETGKTARAVRDMCLEQ 745
            |||.|.|||||:..||.|:|||:||:|.|:|.:..||::|||:||||||||.|||||:||..:..
plant   706 RPVPLGQQYIGINVKKPLRRFQLMNDICYQKVVAVAGKHQVLIFVHSRKETAKTARAIRDTAMAN 770

  Fly   746 DTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLV 810
            |||..||||.|.|.|:|:..|..:||.:|||||||||||||||:||.||.:||:.|...::|||:
plant   771 DTLSRFLKEDSQSREILKCLAGLLKNNDLKELLPYGFAIHHAGLTRTDREIVENQFRWGNLQVLI 835

  Fly   811 STATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSE 875
            |||||||||||||||||||||||||||:|.|:|||.|||:||:|||||||||.:||||:||.:|:
plant   836 STATLAWGVNLPAHTVIIKGTQVYNPERGEWMELSPLDVMQMIGRAGRPQYDQQGEGIIITGYSK 900

  Fly   876 LQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSH 940
            ||:||.|:|:||||||||||||.|.|||||||||:|:.::|.:||||||||:||:|||||||||.
plant   901 LQYYLRLMNEQLPIESQFISKLADQLNAEIVLGTIQNAREACHWLGYTYLYVRMVRNPTLYGVSP 965

  Fly   941 DAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLL 1005
            ||:..|.|||:.||||:|:||..|:::.|||||||:|||||||||||||:||::|.|:..||:.|
plant   966 DALAKDLLLEERRADLIHSAATILDKNNLIKYDRKSGHFQVTDLGRIASYYYISHGTIAAYNENL 1030

  Fly  1006 KQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERVPIPIKESIEEHSAKVNVLLQAYISQL 1070
            |.|:::|||.|:||||.||::::||::||:||.||::|||||:||::|:.|||:|||||.|||:|
plant  1031 KPTMNDIELCRLFSLSEEFKYVTVRQDEKMELAKLLDRVPIPVKETLEDPSAKINVLLQVYISKL 1095

  Fly  1071 KLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQFKKM 1135
            ||||.:|.||||:|||||.||:||||||||.||||||:.|.|.|.||:.:|||...|||.||..:
plant  1096 KLEGLSLTSDMVYITQSAGRLLRAIFEIVLKRGWAQLSQKALNLSKMVGKRMWSVQTPLWQFPGI 1160

  Fly  1136 PDEIAKKLEKKHFPWGRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRGTLRV 1200
            |.||..||||....|.|.|||...||||||..||:|:.:||::||||||:|:.|:|||:|..|:|
plant  1161 PKEILMKLEKNDLVWERYYDLSSQELGELICNPKMGRPLHKYIHQFPKLKLAAHVQPISRSVLQV 1225

  Fly  1201 ELTITPDFQWDEKVHGQSEGFWVLIEDVDSELILHHEFFLLKQKYSQDEHQLKFFVPVFEPLPPQ 1265
            |||:||||.||:|.:...|.||:::||.|.|.|||||:||.|::...::|.|.|.||:.||:|||
plant  1226 ELTVTPDFHWDDKANKYVEPFWIIVEDNDGEKILHHEYFLFKKRVIDEDHTLNFTVPISEPIPPQ 1290

  Fly  1266 YFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQRFPQFNP 1330
            ||:|:|||:|:.:.|.|||||||||||||..||||||||||||:.|||.|.:|:.| |.|..|||
plant  1291 YFIRVVSDKWLDSPTVLPVSFRHLILPEKYPPPTELLDLQPLPVMALRNPSYETLY-QDFKHFNP 1354

  Fly  1331 IQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMR--LFTTQSDARCVYLVSEEALADLVFADW 1393
            :|||||..:||:.:||.|.|||||||...|||||:|  |....|..|.||:...||:|...|.||
plant  1355 VQTQVFTVLYNTSDNVVVAAPTGSGKTICAEFAILRNHLEGPDSAMRVVYIAPLEAIAKEQFRDW 1419

  Fly  1394 HSKFG-SLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQL 1457
            ..||| .|.::||:|||||..||||:.|||::|:|.:|||.|||||||||.:|.|:|||||||.|
plant  1420 EKKFGKGLGLRVVELTGETLLDLKLLEKGQIIISTPEKWDALSRRWKQRKYIQQVSLFIVDELHL 1484

  Fly  1458 VGGEEGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPSVRPIPL 1522
            :||:.|.|||::.|||||||||:..:|||||||.||.:|:|:.:|:|.:....|||.|:|||:||
plant  1485 IGGQGGQVLEVIVSRMRYISSQVGNKIRIVALSTSLANAKDLGEWIGASSCGVFNFPPNVRPVPL 1549

  Fly  1523 ELHIQGYNVTHNATRIATMSKPVYNAILKYSAH-KPVIVFVSSRKQARLTAIDVLTYAASD-LQP 1585
            |:||.|.::.....|:..|:||.|.||::::.: ||.||||.:||..||||:|::.|:..| ::.
plant  1550 EIHIHGVDILSFEARMQAMTKPTYTAIVQHAKNKKPAIVFVPTRKHVRLTAVDLIAYSHMDNMKS 1614

  Fly  1586 NRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLC 1650
            ..|.....|:::|||.::.::||||||..|:.|||||||..|..:|.|||::|.:||.|:|..||
plant  1615 PDFLLGNLEELEPFLIQICEETLKETLRHGIGYLHEGLSNLDQEIVTQLFEAGRIQVCVMSSSLC 1679

  Fly  1651 WGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKK 1715
            ||..:.||||::|.|.||:|:.:|:.||||:::|||:||.:||..|...|||:.|.:.:|:::||
plant  1680 WGTPLKAHLVVVMGTHFYDGRENSHSDYPISNLLQMMGRGSRPLLDDAGKCVIFCHAPRKEYYKK 1744

  Fly  1716 FINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVTHRHL 1780
            |:.|.||:||||.|.:||:||||||.:.|||||||||||||:|:||||.||||||||.||:||||
plant  1745 FLYEALPVESHLQHFLHDNFNAEVVARVIENKQDAVDYLTWSFMYRRLPQNPNYYNLLGVSHRHL 1809

  Fly  1781 SDHLSELVENTLSDLEQSKCISVEDDMDTLPLNLGMIAAYYYINYTTIELFSLSLNSKTKVRGLL 1845
            ||||||||||||||||.||||.:::::|..||||||||:||||||||||.||..|.||||::|||
plant  1810 SDHLSELVENTLSDLEVSKCIEIDNELDLSPLNLGMIASYYYINYTTIERFSSLLASKTKMKGLL 1874

  Fly  1846 EIISSAAEYEDVVVRHHEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAHLSRLQLGP 1910
            ||::||:||:.:.:|..||..:|.|...  .:.:..|   |:..||.:||:.|||||.||.::..
plant  1875 EILTSASEYDLIPIRPGEEDAVRRLINH--QRFSFQN---PRCTDPRVKTSALLQAHFSRQKISG 1934

  Fly  1911 ELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMWSKDSYLKQLPHFSPEIV 1975
            .|..|..::|..|.||:||.|||:||||.|:.|:.|||::|||||.||.:||.|.|||||:.::.
plant  1935 NLVMDQCEVLLSATRLLQAMVDVISSNGCLNLALLAMEVSQMVTQGMWDRDSMLLQLPHFTKDLA 1999

  Fly  1976 KRCTE---KKIETVFDIMELEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGS 2037
            |||.|   ..|||:||::|:||:.|..|||:||.|:.|:||||||:|||:|.||:|..:.::.|.
plant  2000 KRCHENPGNNIETIFDLVEMEDDKRQELLQMSDAQLLDIARFCNRFPNIDLTYEIVGSNEVSPGK 2064

  Fly  2038 TVNVVVQLEREDE---VTGPVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTLQQKAKVKLDFV 2099
            .:.:.|.|||:.|   ..|||.||.:|:.:|||||:|:|:.|||.|::|||::||:||:|||:|.
plant  2065 DITLQVLLERDMEGRTEVGPVDAPRYPKTKEEGWWLVVGEAKTNQLMAIKRISLQRKAQVKLEFA 2129

  Fly  2100 APS-PGKHDYTLYYMSDSYLGCDQEYKFSIEVGDFQSESESE 2140
            .|: .|:..||||:|.||||||||||.|:::|.|..:....|
plant  2130 VPTETGEKSYTLYFMCDSYLGCDQEYSFTVDVKDSDAADHME 2171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Brr2	NP_648818.3	Helicase_PWI	259..368	CDD:436309	48/112 (43%)
		DEXHc_Brr2_1	464..677	CDD:350777	126/212 (59%)
		BRR2	476..1020	CDD:440817	354/543 (65%)
		Sec63	982..1285	CDD:460740	180/302 (60%)
		BRR2	1309..1848	CDD:440817	311/543 (57%)
		DEXHc_Brr2_2	1325..1514	CDD:350779	110/191 (58%)
		Sec63	1811..2127	CDD:460740	171/322 (53%)
AT2G42270	NP_181756.1	Helicase_PWI	265..377	CDD:436309	48/112 (43%)
		BRR2	488..1019	CDD:440817	347/530 (65%)
		DEXHc_Brr2_1	489..702	CDD:350777	126/212 (59%)
		Sec63	1007..1310	CDD:460740	180/302 (60%)
		BRR2	1349..1877	CDD:440817	304/527 (58%)
		DEXHc_Brr2_2	1349..1540	CDD:350779	109/190 (57%)
		SEC63	1837..2160	CDD:214744	173/327 (53%)