Protein Alignment l(3)72Ab and obe

DIOPT Version :9

• Sequence 1: NP_648818.3
• Gene: l(3)72Ab / 39737
• FlyBaseID: FBgn0263599
• Length: 2142
• Species: Drosophila melanogaster
• Sequence 2: NP_650472.2
• Gene: obe / 41891
• FlyBaseID: FBgn0038344
• Length: 2183
• Species: Drosophila melanogaster
• Alignment Length: 2243
• Identity: 811/2243 - (36%)
• Similarity: 1251/2243 - (55%)
• Gaps: 272/2243 - (12%)

  Fly    59 TKPEKTEERKVKR-------QKRDEAQYDFERMKGATLLSEGIDEMVGIVYRPKTQETRQTYEVL 116
            |..:..||:.:.|       :|:..|:...::::..      :.|.:|.      :|..|..|..
  Fly    40 TNSQNKEEQTIARLLAQMPTEKQPAAKVQLQKLRNL------VQECMGY------EEQPQVVEHA 92

  Fly   117 LSFIQEALGDQPRDILCGAADEILAVLKNDRLK-------DRERKKDIDSLLGAVTDERFALLVN 174
            ..|:...|.||          .:|.|....||.       || :|..|...:.|:
  Fly    93 ALFLFWLLLDQ----------RVLLVATTQRLHGMFGQTFDR-KKTQIHDCVQAI---------- 136

  Fly   175 LGKKITDFGSDAVNALTAAPNNEEQIDETYGINVQFEESEEE-SDNDMYGEIRDDDAQDEG--EE 236
             |..:.|....|:.......:....:...:|.::..:.:..| .|..:..::..|......  .:
  Fly   137 -GDLLEDHERSALKRWRQTHHKVPGVGPLWGAHIHVKCTPSEWMDISLLTDLAPDALLKNRTVNK 200

  Fly   237 ARIDHTLHAENLA--NEEAANNVKKERSLHPLDIDAYWLQRCLSKFYKDAMVSQSKAADVLKILK 299
            ..:.||..|..:|  :.|||....:.::|  |:|.|......|.....|.:.|| ::::||
  Fly   201 FSMKHTTKAAPVASTSSEAAKLSPELQTL--LEISAKLDDEHLIIRVGDILGSQ-RSSEVL---- 258

  Fly   300 DAADDRDCENQLVLLLGYDCFDFIKQL-----KLNRQMVLYCT---------------------- 337
                    :|:|:.:||:|.|:.:::|     |:.||:..:.|
  Fly   259 --------QNELMEILGFDYFELVEKLLMERDKIARQLDQFATRSRRVMEVKQKRMEAAASGGAA 315

  Fly   338 ----MLASA---QTDSERQRIREKMRGNSALAKILRQLDTGKSEDQEEGEARGSKRGKGDAEDGG 395
                .:|||   |:..|:|..:.:.|....|.:|:|.:...::||                 |..
  Fly   316 ERRPTVASAVVVQSAQEKQLSKMQRREEKKLQRIMRSIKDEEAED-----------------DPN 363

  Fly   396 AAAAGQVAGV-----RQLL-----------------ELEEMAFTQGSH----------------F 422
            .|.|..|..:     |:||                 |.::.::.|..|                |
  Fly   364 CAVAVSVQQLRMQHQRKLLEAAQREPLLLSTKAAKAEYKQSSYNQPIHYPYVFDSQLLAKQHAGF 428

  Fly   423 MANKRCQLPDGSYRKQRKGYEEVHVPALKPVPFDANEELQPVDKLPKYVQPVFEGFKTLNRIQSR 487
            :...|..|||.:.|...|.:|||.:||.:|.|.....:...:::|....:..|...|.||||||.
  Fly   429 IGGSRITLPDNAQRIDNKQWEEVKIPASEPPPLSVGNKRVQIEELDDVGRLAFANCKELNRIQSV 493

  Fly   488 LYKAALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQEMV 552
            ::..|..|:||||:||||||||||||:|:::..|..|: |.|.||..:|||:|:||||:|..|||
  Fly   494 VFPVAYHSNENMLVCAPTGAGKTNVAMLSIVHTIRCHL-EQGVINRDEFKIVYIAPMKALAAEMV 557

  Fly   553 GNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKG-GERTFVSLVRLVIIDE 616
            .||.:||....:.|.|||||.|||:.::||||::|.||||||::|||| |:...:|||.|:||||
  Fly   558 DNFSKRLKSLQIAVRELTGDIQLTKAEMAATQILVTTPEKWDVVTRKGSGDVALISLVELLIIDE 622

  Fly   617 IHLLHDERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYR 681
            :||||.|||||:|||||||:|.:|::|..:|:||||||||||.|||.||||.|.|||||||:.:|
  Fly   623 VHLLHGERGPVVEALVARTLRLVESSQSMIRIVGLSATLPNYIDVAHFLRVNPMKGLFYFDSRFR 687

  Fly   682 PVSLEQQYIGVTEKKALKRFQVMNEIVYEKTMEHAGR-NQVLVFVHSRKETGKTARAVRDMCLEQ 745
            ||.|:..::|:...|.|::...|::..|:|.:|.... :|::||||:|..|.:||..:|::..:.
  Fly   688 PVPLDTNFVGIKSVKQLQQIADMDQCCYQKCVEMVQEGHQIMVFVHARNATVRTANVIRELAQQN 752

  Fly   746 DTLGSFLKEGSASMEVLRTEAEQVKNTELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLV 810
            :|...||.:.||:..:.....::.:|.:|.||...|.|:|||||.|.||.:||..|.:.||.|||
  Fly   753 NTSALFLPKDSAAHGLATRSIQRSRNKQLVELFSCGLAMHHAGMLRADRQMVEKYFVEGHISVLV 817

  Fly   811 STATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHSE 875
            .|||||||||||||.|||:||.:|:.:.|.:|:|..|||||:.|||||||:|..|.|.:||::.:
  Fly   818 CTATLAWGVNLPAHAVIIRGTDIYDAKHGSFVDLGILDVLQIFGRAGRPQFDKSGVGTIITSYDK 882

  Fly   876 LQFYLSLLNQQLPIESQFISKLPDMLNAEIVLGTVQHLQDAVNWLGYTYLYIRMLRNPTLYGVSH 940
            |..|||||..|.||||.|::.|.|.|||||.|||:.::.:|:.||.||||::||..||.:||:.:
  Fly   883 LNHYLSLLTNQFPIESNFVNCLADNLNAEIGLGTITNVDEAIEWLSYTYLFVRMRINPHVYGIEY 947

  Fly   941 DAIKADPLLEQHRADLLHTAACCLERSGLIKYDRKTGHFQVTDLGRIASHYYLTHETMLTYNQLL 1005
            ..::.||.||..|..|:.:||..|:::.:::::::|....:|||||.||::|:.::|:.|:|:|:
  Fly   948 SELEKDPTLEARRRALIMSAAMSLDKARMMRFNQRTMDMNITDLGRTASYFYIKYDTVETFNELM 1012

  Fly  1006 KQTLSEIELFRVFSLSSEFRHISVREEEKLELQKLMERV----PIPIKESIEEHSAKVNVLLQAY 1066
            |..:::.|:..:.|.:.||:.:.||::|..||.:|....    |....|::.   .|||:|:|.|
  Fly  1013 KPFMTQAEILAMISQAQEFQQLKVRDDEMEELDELKNAYCKIKPYGGSENVH---GKVNILIQTY 1074

  Fly  1067 ISQLKLEGFALMSDMVFITQSAARLMRAIFEIVLTRGWAQLADKTLTLCKMIDRRMWQSMTPLRQ 1131
            :|...::.|:|.|||.:||.:..|:.||:|.|||.:..|.|:...|.||||.:||.|.....|:|
  Fly  1075 LSNGYVKSFSLSSDMSYITTNIGRISRALFSIVLRQNNAVLSGNMLQLCKMFERRQWDFDCHLKQ 1139

  Fly  1132 FKKMPDEIAKKLEKKHFPWGRLYDLEPHELGELIRVPKLGKTIHKFVHQFPKLELSTHIQPITRG 1196
            |..:..|...|||::.....||.|:|..||.|.:|.......:.:..|:.|.||:...:|||||.
  Fly  1140 FPTINAETIDKLERRGLSVYRLRDMEHRELKEWLRSNTYADLVIRSAHELPLLEVEASLQPITRT 1204

  Fly  1197 TLRVELTITPDFQWDEKVHGQS-EGFWVLIEDVDSELILHHEFFLLKQK--YSQDEHQLKFFVPV 1258
            .||:::.|.|.|.|:::|||:: :.||:.|||.:|..|.|.|.|.:.:|  .|....||...:|:
  Fly  1205 VLRIKVDIWPSFTWNDRVHGKTCQSFWLWIEDPESNYIYHSELFQVTRKLVMSGQSQQLVMTIPL 1269

  Fly  1259 FEPLPPQYFLRIVSDRWIGAETQLPVSFRHLILPEKNMPPTELLDLQPLPISALRQPKFESFYSQ 1323
            .|||||||::|:.||.|:|:.|.:|:||:||:|||.:.|.||||.|:|||:|.|:...:||.|
  Fly  1270 KEPLPPQYYIRVSSDNWLGSTTCIPLSFQHLVLPEHHPPLTELLPLRPLPVSCLKNVVYESLY-- 1332

  Fly  1324 RFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADL 1388
            :|..|||||||:|:.:|::|.||.:||||||||..:||.||.|........:.||:...:||...
  Fly  1333 KFTHFNPIQTQIFHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKE 1397

  Fly  1389 VFADWHSKF--GSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFI 1451
            ..|||..:|  .||.:|||:|||:...|::.|.:.||::||.:|||.:||.|:.|:.||.|:|.:
  Fly  1398 RIADWEQRFQRSSLGLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIV 1462

  Fly  1452 VDELQLVGGEEGPVLEIVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNFHPS 1516
            :||:.|:|.:.|||:|::.||..:|||...:.||||.||.:|.:|:|:|.|||.|....:||.||
  Fly  1463 IDEIHLLGEDRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKPS 1527

  Fly  1517 VRPIPLELHIQGYNVTHNATRIATMSKPVYNAILKYSAHKPVIVFVSSRKQARLTAIDVLTYAAS 1581
            |||:||::||.|:...|...|:|||::|.:.||..||..:|.|||||||:|.||||:|::|:.|.
  Fly  1528 VRPVPLQVHINGFPGKHYCPRMATMNRPTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAG 1592

  Fly  1582 DLQPNRFFHAEEEDIKPFLERMTDKTLKETLAQGVAYLHEGLSASDHRLVEQLFDSGAVQVAVIS 1646
            :..|.:|.|..|::|:..|:.:.::.||..||.|:...|.||...|.:.||:||.:..:|:.|.:
  Fly  1593 ESNPKQFLHIPEDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVAT 1657

  Fly  1647 RDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKD 1711
            ..|.||:::.||||:|..|::::||...|.|.||||||||:|||.||..|.:...|::....||:
  Fly  1658 ATLAWGVNLPAHLVVIKGTEYFDGKVKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKN 1722

  Fly  1712 FFKKFINEPLPIESHLDHRMHDHFNAEVVTKTIENKQDAVDYLTWTFLYRRLTQNPNYYNLQGVT 1776
            |:|||:.:|.|:||.|...:.:|.|||:|..|:::||.|:||||||:.:|||.:||:||.||.:.
  Fly  1723 FYKKFLYDPFPVESSLLGVLPEHINAEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQDIE 1787

  Fly  1777 HRHLSDHLSELVENTLSDLEQSKCISVEDDMDTLPLNLGMIAAYYYINYTTIELFSLSLNSKTKV 1841
            ..::::.:|.|||..:.:|..:.|: ||.|...:|..||.|::|||::|.|::.|...|......
  Fly  1788 PENVNNFMSNLVERVVYELSAAACL-VERDGCLIPTFLGRISSYYYLSYRTMKHFLEDLQPGMNT 1851

  Fly  1842 RGLLEIISSAAEYEDVVVRH----HEEQVLRTLSQRLPNKLTGPNETAPKFNDPHIKTNLLLQAH 1902
            :.:|..|:.:.|::.:.|||    |.|::......|.|:.         .::..:.||.||||||
  Fly  1852 KKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSS---------SWDSSYTKTFLLLQAH 1907

  Fly  1903 LSRLQL-GPELQGDTEQILSKAIRLIQACVDVLSSNGWLSPAVAAMELAQMVTQAMW-------- 1958
            .:|..| ..:...||:..|..|.|::||.||..:..||||..:...:|.|.|.||.|
  Fly  1908 FARQSLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLMQSVIQARWFDGSEFLT 1972

  Fly  1959 -------SKDSYLKQLPHFS------PEIVKRC---------------TEKKIETVFDIME---- 1991
                   :.|::| .:||..      |.:.:.|               .|.:||.::.:::
  Fly  1973 LPGVNEDNLDAFL-NIPHDDYDYLTLPVLKELCKQEYEVLAKPLRDAFEEHEIEKMYKVIQDLPE 2036

  Fly  1992 -----------LEDEDRTRLLQLSDLQMADVARFCNRYPNIELNYEVVDKDRINSGSTVNVVVQL 2045
                       :|:|...|.|.|||....:       :.::..|.:.|            ::|.|
  Fly  2037 IAIQIFVEGRHMENEYAKRPLSLSDDTRGE-------WMSLHANEDYV------------LIVNL 2082

  Fly  2046 EREDEVTG---------PVIAPFFPQKREEGWWVVIGDPKTNSLLSIKRLTLQ-QKAKVKLDFVA 2100
            :|.: |:|         .|..|.:|:.:.|.|::.:|....:.||::||:::: |:...::.|.|
  Fly  2083 QRLN-VSGQRRGGGQSYTVHCPKYPKPKNEAWFLTLGSQANDELLAMKRVSIRGQRCTNRISFQA 2146

  Fly  2101 -PSPGKHDYTLYYMSDSYLGCDQEYKFSIEVGD 2132
             |..|:...|||.|||..:|.||:|....|:.|
  Fly  2147 TPRLGRLQLTLYLMSDCLMGFDQQYDLQFEIID 2179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(3)72Ab	NP_648818.3	BRR2	466..1241	CDD:224125	359/781 (46%)
		DEAD	482..661	CDD:278688	109/179 (61%)
		HELICc	773..859	CDD:197757	52/85 (61%)
		Sec63	982..1285	CDD:280962	118/309 (38%)
		DEXDc	1320..1506	CDD:214692	86/187 (46%)
		DEAD	1329..1495	CDD:278688	77/167 (46%)
		HELICc	1615..1694	CDD:197757	36/78 (46%)
		Sec63	1811..2127	CDD:280962	98/382 (26%)
obe	NP_650472.2	BRR2	450..1254	CDD:224125	365/807 (45%)
		DEAD	488..666	CDD:278688	109/178 (61%)
		HELICc	790..866	CDD:197757	48/75 (64%)
		Sec63	989..1296	CDD:280962	118/309 (38%)
		DEXDc	1332..1532	CDD:214692	94/201 (47%)
		DEAD	1338..1510	CDD:278688	78/171 (46%)
		HELICc	1605..1704	CDD:197757	41/98 (42%)
		SEC63	1818..2176	CDD:214744	98/387 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466316
Domainoid	1	1.000	58	1.000	Domainoid score	I607
eggNOG	1	0.900	-	-		E1_COG1204
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D154891at2759
OrthoFinder	1	1.000	-	-		FOG0001085
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100305
Panther	1	1.100	-	-	P	PTHR24075
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.750