Protein Alignment elgi and TRAF6

DIOPT Version :9

• Sequence 1: NP_001261904.1
• Gene: elgi / 39735
• FlyBaseID: FBgn0283649
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_004611.1
• Gene: TRAF6 / 7189
• HGNCID: 12036
• Length: 522
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 59/326 - (18%)
• Similarity: 98/326 - (30%)
• Gaps: 132/326 - (40%)

  Fly     2 GYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWL-TRQPTCPVDRNSLTTANL 65
            |||| .|...::.:..||||...|.:.:| ..|.|.||:.||.:.: .....||||...|....|
Human    55 GYDV-EFDPPLESKYECPICLMALREAVQ-TPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQL 117

  Fly    66 RAVPRILRNLLS----------------------------------------------------- 77
            .......|.:||
Human   118 FPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDC 182

  Fly    78 -RLSITCDNAPYG----------------------CTAVLKLDAYNSHLD-ECIHNPKRPFPC-- 116
             |..::|||....                      |..:|..:...:|.| :|   |..|.||
Human   183 PRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDC---PTAPIPCTF 244

  Fly   117 -EKGCGFDIPKDELKDH-----------------------------------NCVRELRTLIVKQ 145
             ..||...:.::.|..|                                   ..:.:|...:|:|
Human   245 STFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQ 309

  Fly   146 TEKMGELKSELTDQQLTINELKRELQLFKDFMRAM-----------RVSNPAMRAIADQMERDEV 199
            ..::.||.:::..|.:.::||||.::..:|.:..:           ::.|..|.....:.|:..|
Human   310 DHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVV 374

  Fly   200 I 200
            |
Human   375 I 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	13/38 (34%)
		Sina	83..>157	CDD:302762	21/134 (16%)
		USP8_interact	137..315	CDD:286082	16/75 (21%)
TRAF6	NP_004611.1	Interaction with TAX1BP1. /evidence=ECO:0000269|PubMed:10920205	1..354		54/303 (18%)
		RING	69..107	CDD:238093	13/38 (34%)
		zf-TRAF	204..261	CDD:280357	12/59 (20%)
		MATH_TRAF6	351..500	CDD:239745	5/25 (20%)
		Interaction with TANK. /evidence=ECO:0000269|PubMed:25861989	355..522		5/21 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820