Protein Alignment elgi and trim8

DIOPT Version :10

• Sequence 1: NP_648816.1
• Gene: elgi / 39735
• FlyBaseID: FBgn0283649
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001027512.1
• Gene: trim8 / 613104
• XenbaseID: XB-GENE-1006787
• Length: 551
• Species: Xenopus tropicalis
• Alignment Length: 389
• Identity: 76/389 - (19%)
• Similarity: 142/389 - (36%)
• Gaps: 141/389 - (36%)

  Fly    13 DEELTCPICSGVLEDPLQAVMCEHAFCRGCINE-W-----LTRQPTCPVDRNSLTT--ANLRAVP 69
            :|||.||||..|..:|:| :.|:|.||||||:| |     :.|.|.|....|...|  .||:
 Frog    10 EEELICPICLHVFIEPVQ-LPCKHNFCRGCISEAWAKETGMVRCPECNQAYNQKPTLEKNLK--- 70

  Fly    70 RILRNLLSRL-SITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGC------------- 120
              |.|::.:. |:..|.||    ::|       |...|...|  |.|.:|.|
 Frog    71 --LTNIVEKFNSLNVDKAP----SIL-------HCVFCRRGP--PLPAQKICLRCEAPCCQSHVQ 120

  Fly   121 ----------------GFDIPKDELKDHNCVR--------------------------------- 136
                            ..|:.......||..|
 Frog   121 THLQQPSTARGHLLVEAEDVRAWSCPQHNAYRLYHCEAEQVAVCQFCCYYSGAHQGHSVCDVEIR 185

  Fly   137 --ELRTLIVKQTEKMGELKSELTDQ-----------QLTINELKRELQ---------LFKDFMRA 179
              |:|.:::||.:::.|.:.::.||           :..:::||.|::         |.:|..:.
 Frog   186 RNEIRKMLIKQQDRLEEREQDIEDQLYKLESDKRLVEEKVSQLKDEVRQQYDKLHQILDEDLRKT 250

  Fly   180 MRVSNPAMRAIADQMERDEVIRWSSTLPRAR--VTRWGGMISTPDD--------ALQLMIKRALS 234
            |.:.:.|.....:: ...:|::.:..:..|:  ::....|....:|        ::::::.|..:
 Frog   251 MDILDKAQAKFCNE-NAAQVLQLNERMQEAKKLLSSVQVMFDKTEDINFMKNTKSVKILMDRTQN 314

  Fly   235 ESG--CPP----HILDSLMEFCHERRWPRGLSSLETRQTN-RRIYDNYVCRRIPGKQAVLVLSC 291
            .:|  .||    |:...|.           ||.:..::.. |::.:......:|..|::.:.||
 Frog   315 CTGGSLPPPKIGHLNSKLF-----------LSEIAKKEKQLRKMLEGPFNTPVPFLQSIPMYSC 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_648816.1	mRING-HC-C3HC3D_Nrdp1	15..57	CDD:438296	22/47 (47%)
		USP8_interact	137..315	CDD:430333	31/192 (16%)
trim8	NP_001027512.1	RING-HC_TRIM8_C-V	2..68	CDD:438242	25/58 (43%)
		Bbox1_TRIM8_C-V	90..137	CDD:380896	8/55 (15%)
		Bbox2_TRIM8_C-V	142..183	CDD:380821	3/40 (8%)
		PRK12704	181..>280	CDD:237177	15/99 (15%)