DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment elgi and traf5

DIOPT Version :9

Sequence 1:NP_001261904.1 Gene:elgi / 39735 FlyBaseID:FBgn0283649 Length:315 Species:Drosophila melanogaster
Sequence 2:XP_021325328.1 Gene:traf5 / 563887 ZFINID:ZDB-GENE-071120-3 Length:542 Species:Danio rerio


Alignment Length:383 Identity:78/383 - (20%)
Similarity:123/383 - (32%) Gaps:137/383 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 RFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTR--QPTCPVDRNSLTTANLRAVP 69
            ||...::::..||.|.|::.:|.| ..|.|.||..|:..:...  ...||:|...:....:....
Zfish    30 RFVSRLEQQFICPSCGGIVLNPHQ-TGCGHIFCAQCVKAYTENGGSSKCPLDSIPIKPEEIFQDN 93

  Fly    70 RILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHN------------------------- 109
            ...|.||: |.:.|.||| .||....|.....||..|.|.                         
Zfish    94 CCKRELLN-LEVFCTNAP-ECTQRFSLCNLQDHLKACPHERVRCSHSDCSDIVLRKNLLEHQRNA 156

  Fly   110 ----------------------------PKRPFPCEKGCGFDIPKDEL----------------K 130
                                        |....||...|...|.:.:|                |
Zfish   157 CSYRLETCHYCRQNFPVSQMMGHQKSSCPDVEVPCSNNCTQMIKRHQLQAHADECLEVETDCVYK 221

  Fly   131 DHNC-----------------------VRELRTLIVKQTEKMGE----LKSELTDQQLTINELKR 168
            ::.|                       |.|..|.:.||.|::.:    .:..|.|:.|.::.|.|
Zfish   222 NYGCTVRDKRGKVQVHENTEFSAHVRLVLESNTKLEKQMEQLQQDMLVQQGVLKDKSLVVSSLDR 286

  Fly   169 ELQLFKDFMRAMR--VSNPAMRAIADQME-RDEVIRWS---STLPRARVTRWGGMISTPDDAL-- 225
            ::.|..:.:..::  |....:|..:.|.| ||..:..|   ..|||.:.:.         |:|  
Zfish   287 DVSLCDNTLTTLQRSVEEQRVRICSVQRELRDLRVLGSELKEELPRLQASL---------DSLRQ 342

  Fly   226 QLMIKRALS------ESGCPPH--ILDSLME--FCHERRWPRGLSSLETRQTNRRIYD 273
            |:.:..:|.      |..|..|  :||..:|  .|:|:|         .||.....||
Zfish   343 QVAVTESLREHLGALEQTCERHTRLLDIHVEQLQCNEQR---------LRQLESSSYD 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
elgiNP_001261904.1 RING 17..55 CDD:238093 12/39 (31%)
Sina 83..>157 CDD:302762 25/169 (15%)
USP8_interact 137..315 CDD:286082 38/159 (24%)
traf5XP_021325328.1 RING_Ubox 39..80 CDD:327409 13/41 (32%)
zf-TRAF 124..179 CDD:280357 4/54 (7%)
zf-TRAF 179..237 CDD:280357 8/57 (14%)
SMC_N <238..>387 CDD:330553 37/166 (22%)
MATH_TRAF_C 392..535 CDD:238168 78/383 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D918518at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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