DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and traf2b

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_005165556.1	Gene:	traf2b / 557526	ZFINID:	ZDB-GENE-030131-5345	Length:	532	Species:	Danio rerio

Alignment Length:	215	Identity:	50/215 - (23%)
Similarity:	75/215 - (34%)	Gaps:	36/215 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQP----TCPVD---RNSLTTANLR-AV 68
            ::.:..|..|..:|..|.|| .|.|.||..|..:..:..|    .|..:   ....:..|:. |.
Zfish    39 MEPKYQCQQCKDILRKPFQA-QCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEEETSVLNIAVAF 102

  Fly    69 P-RILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDI---PKDEL 129
            | ...|..:..|...|.|.....:..|| |..|.|...|.....:   || .|...|   .||..
Zfish   103 PDNAARREIDSLPAKCPNEGCSWSGTLK-DFENQHEGRCAFERVK---CE-ACQVLILLSEKDRH 162

  Fly   130 KDHNCVRELRTL---IVKQTEKMGELKS------ELTDQQLTINELKRELQLFKDFMRAMRVSNP 185
            .:..|  |.|||   ..|.|....|:|:      :...|.....:.|...:.|::..::...|..
Zfish   163 NEREC--EARTLNCKYCKVTFNFKEIKAHDEICQKFPMQCKDCGKKKIPREKFQEHTKSCAKSKS 225

  Fly   186 A-------MRAIADQMERDE 198
            |       .||:.|..::.|
Zfish   226 ACQFREIGCRAVVDNCKQQE 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	13/41 (32%)
		Sina	83..>157	CDD:302762	23/85 (27%)
		USP8_interact	137..315	CDD:286082	17/78 (22%)
traf2b	XP_005165556.1	RING	44..86	CDD:238093	13/42 (31%)
		zf-TRAF	189..246	CDD:280357	9/57 (16%)
		TRAF_BIRC3_bd	307..359	CDD:293278
		MATH_TRAF2	365..528	CDD:239747
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010