DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and traf4a

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_991325.1	Gene:	traf4a / 404045	ZFINID:	ZDB-GENE-040308-1	Length:	470	Species:	Danio rerio

Alignment Length:	132	Identity:	37/132 - (28%)
Similarity:	61/132 - (46%)	Gaps:	6/132 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQP-TCPVDRNSLTTANL 65
            |:|. :|..:......||:||..:.:|:|...|.|.||..|:.|:|:... .||.|:..|..|.:
Zfish     3 GFDY-KFLEKPKRRFQCPLCSKAMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKI 66

  Fly    66 RAVPRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDIPKDELK 130
            ...|.:.:.:|: |.|.|.::..||....::....||...|..|   ..||...|...:.:.:|.
Zfish    67 YPDPELEQQILA-LPIRCIHSEEGCRWTGQMKQLQSHFSTCAFN---VIPCPNRCSVKLTRRDLP 127

  Fly   131 DH 132
            :|
Zfish   128 EH 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	14/38 (37%)
		Sina	83..>157	CDD:302762	12/50 (24%)
		USP8_interact	137..315	CDD:286082
traf4a	NP_991325.1	RING	17..55	CDD:238093	13/37 (35%)
		zf-TRAF	102..156	CDD:280357	8/31 (26%)
		zf-TRAF	156..210	CDD:280357
		zf-TRAF	210..269	CDD:280357
		MATH_TRAF4	308..463	CDD:239750
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820