DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and traf4b

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_997982.1	Gene:	traf4b / 404035	ZFINID:	ZDB-GENE-040305-2	Length:	478	Species:	Danio rerio

Alignment Length:	141	Identity:	42/141 - (29%)
Similarity:	65/141 - (46%)	Gaps:	13/141 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQP-TCPVDRNSLTTANL 65
            |.|: :|......:..||:|...:.:|:|...|.|.||..|:.|:|:... |||.|:..|..|.:
Zfish     3 GLDL-KFLERPRRKFYCPLCEKPMREPVQVSTCGHRFCDTCLQEYLSEGVFTCPEDQLPLDYAKI 66

  Fly    66 RAVPRILRNLLSRLSITCDNAPYGC--TAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDIPKDE 128
            .....:.:.:|| |.|.|.::..||  ||..||  ..:||..|..|   ...|...|...:.:.|
Zfish    67 FPDLELEQQILS-LPIRCIHSEEGCRWTAQNKL--LQAHLSVCEFN---VVSCPNRCSVKLLRRE 125

  Fly   129 LKD---HNCVR 136
            |.:   |:|.:
Zfish   126 LPEHLQHDCAK 136

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	14/38 (37%)
		Sina	83..>157	CDD:302762	17/59 (29%)
		USP8_interact	137..315	CDD:286082	42/141 (30%)
traf4b	NP_997982.1	RING	18..55	CDD:238093	13/36 (36%)
		zf-TRAF	102..156	CDD:280357	10/38 (26%)
		zf-TRAF	156..210	CDD:280357
		zf-TRAF	210..269	CDD:280357
		MATH_TRAF4	308..471	CDD:239750
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820