DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and Traf2

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001101285.1	Gene:	Traf2 / 311786	RGDID:	1310457	Length:	497	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	53/299 - (17%)
Similarity:	93/299 - (31%)	Gaps:	107/299 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQP-TCPV--------DR 57
            |:........::.:..|..|..:|..|.|| .|.|.:|..|:...|:..| .|..        :.
  Rat    18 GFSKTLLGTRLEAKYLCSACRNILRRPFQA-QCGHRYCSFCLTSILSSGPQNCAACVHEGLYEEG 81

  Fly    58 NSLTTANLRAVPRILRNLLSRLSITCDN-------------------APY------GCTAVLKLD 97
            .|:..::........|..:..|...|.|                   .|:      .|..:::|.
  Rat    82 ISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLS 146

  Fly    98 AYNSHLDE---------------CIHN---------PKRPFPCEKGCGFDIPKDELKDH--NCVR 136
            ....|.::               |.|.         ||.|..|: |||..|.:::|:||  .|.:
  Rat   147 EKKHHTEQECPKRSLSCQHCRAPCSHADLELHYEVCPKFPLTCD-GCGKKISQEKLQDHVRTCSK 210

  Fly   137 ------------------------ELRTLIVKQTEKMGELKSELTDQQLTINELKREL------- 170
                                    ||:.|    .|.:..|.|...:.|.:.|::..||
  Rat   211 CRVLCRFHAIGCSELVETEDLQDHELQRL----REHLALLLSSFLESQASQNQVGPELLQRCQIL 271

  Fly   171 -QLFKDFMRAMRVSNPAMRAIA---------DQMERDEV 199
             |....|...:.|.|..:..:|         .::::|::
  Rat   272 EQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKI 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	13/38 (34%)
		Sina	83..>157	CDD:302762	26/148 (18%)
		USP8_interact	137..315	CDD:286082	16/80 (20%)
Traf2	NP_001101285.1	RING-HC_TRAF2	32..73	CDD:319553	13/41 (32%)
		zf-TRAF	178..234	CDD:280357	12/56 (21%)
		TRAF_BIRC3_bd	265..325	CDD:406958	6/46 (13%)
		MATH_TRAF2	330..493	CDD:239747
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910