DRSC/TRiP Functional Genomics Resources

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Protein Alignment elgi and Lnx1

DIOPT Version :9

Sequence 1:NP_001261904.1 Gene:elgi / 39735 FlyBaseID:FBgn0283649 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001153049.1 Gene:Lnx1 / 16924 MGIID:1278335 Length:728 Species:Mus musculus


Alignment Length:325 Identity:68/325 - (20%)
Similarity:129/325 - (39%) Gaps:47/325 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 EVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQPTCPVDRNSLTTANLRAVPRILRNL 75
            :||::|.|.||...|.|||. ..|.|.:|..|:..:|..:..|||||..:...:.:....::..|
Mouse    38 DVDDDLICHICLQALLDPLD-TPCGHTYCTLCLTNFLVEKDFCPVDRKPVVLQHCKKSSILVNKL 101

  Fly    76 LSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDIPKDELK------DHNC 134
            |::|.:||....: ||.||:......|...         .|:....:.:.||..:      ...|
Mouse   102 LNKLLVTCPFTEH-CTEVLQRCDLQHHFQT---------SCKGASHYGLTKDRKRRSQDGCPDGC 156

  Fly   135 VRELRTLIVKQTEKMGELKSELTDQQLTIN-------ELKRELQLFKDFMRAMRV-SNPAMRAIA 191
            ...:.|.:..:......: |.:||:....|       |....:....|..|:.|. :.|..|:..
Mouse   157 ASLMATTLSPEVSAAATI-SLMTDEPGLDNPAYVSSVEDGEPVANSSDSGRSNRTRARPFERSTM 220

  Fly   192 DQMERDEVIRWSSTLPRARVTRWGGMISTPDDALQLMIKRALSESGCPPHILDSLMEFCHERRWP 256
            ......::.|..|.|.|   |:.|.:::...|.     .|..||:...|.:...|....     |
Mouse   221 RSRSFKKINRALSALRR---TKSGSVVANHVDQ-----GRDNSENTTVPEVFPRLFHLI-----P 272

  Fly   257 RG-LSSLETRQTNRRIYDNYVCRRIPGKQAVLV-LSCDNLH----MTEDVMIDPGLVMIFAHGIE 315
            .| ::|::..:.:..  ::...|.:.|.:..|| :...:::    :..|..:.||.:::..:|::
Mouse   273 DGEITSIKINRADPS--ESLSIRLVGGSETPLVHIIIQHIYRDGVIARDGRLLPGDIILKVNGMD 335

  Fly   316  315
            Mouse   336  335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
elgiNP_001261904.1 RING 17..55 CDD:238093 13/37 (35%)
Sina 83..>157 CDD:302762 12/79 (15%)
USP8_interact 137..315 CDD:286082 34/191 (18%)
Lnx1NP_001153049.1 mRING-HC-C3HC3D_LNX1 42..83 CDD:319693 16/41 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..220 7/34 (21%)
NPXY motif 185..188 1/2 (50%)
Interaction with MAGEB18. /evidence=ECO:0000250 186..244 12/60 (20%)
PDZ_signaling 276..360 CDD:238492 9/62 (15%)
PDZ_signaling 384..464 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 481..500
PDZ_signaling 506..589 CDD:238492
PDZ_signaling 637..721 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0297
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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