DRSC/TRiP Functional Genomics Resources

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Protein Alignment elgi and traf3

DIOPT Version :9

Sequence 1:NP_001261904.1 Gene:elgi / 39735 FlyBaseID:FBgn0283649 Length:315 Species:Drosophila melanogaster
Sequence 2:XP_002938036.2 Gene:traf3 / 100498216 XenbaseID:XB-GENE-968262 Length:569 Species:Xenopus tropicalis


Alignment Length:377 Identity:83/377 - (22%)
Similarity:137/377 - (36%) Gaps:93/377 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 GYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWL-TRQPTCPVDRNSLTTANL 65
            ||. .||...|:|:..|..|..||.:|.| ..|.|.||..|:|..| :..|.|....:::|...:
 Frog    41 GYK-ERFLKPVEEKYKCEKCRLVLCNPRQ-TECGHRFCETCMNAILSSTSPQCMACEDNITKDKV 103

  Fly    66 RAVPRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHL-DEC----IHNPK-------------- 111
            .......|.:|: |.:.|.|...||..::.|.....|| .:|    :..|:              
 Frog   104 FKDNCCRREVLA-LQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSD 167

  Fly   112 --------RPFPCEKGCGFDIPKDELKDHNCVRELRTLIVK---QTEKMGELKSEL--------- 156
                    |..|| |.|...:|..|::.|..| :..::::.   .......|:|||         
 Frog   168 HIEKTCKYRETPC-KFCRNQVPLVEMQKHEDV-DCPSVVISCPHMCSVKSLLRSELNAHLLECVN 230

  Fly   157 ----------------TDQQLTINELKRELQ---LFKDFMRAM--RVS---------NPAMRAIA 191
                            |:||:..:|....:|   |.|::...:  :||         |.:::.:.
 Frog   231 APSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILH 295

  Fly   192 DQM--ERDEVIRWSSTL--PRARVTRWGGMISTPDDALQLMIK--RALSESGCPPHILDSLMEFC 250
            :||  ...|:.|....|  ..||:.:...:|....|.|:.:.|  |.|.::|.....:.|..|..
 Frog   296 NQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESL 360

  Fly   251 HERRWPRGLSSLETRQTNRRIYDNYVCRRIPGKQAVLVLSCDNLHMTEDVMI 302
            ..|     ||.||....|...::       ||.....:...|.:....|:.:
 Frog   361 QNR-----LSQLEVMAKNAASWN-------PGVLETQINRHDQMLSVHDIRL 400

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
elgiNP_001261904.1 RING 17..55 CDD:238093 15/38 (39%)
Sina 83..>157 CDD:302762 22/128 (17%)
USP8_interact 137..315 CDD:286082 40/214 (19%)
traf3XP_002938036.2 RING-HC_TRAF3 54..95 CDD:319554 15/41 (37%)
RING-HC finger (C3HC4-type) 56..94 CDD:319554 15/38 (39%)
zf-TRAF 139..195 CDD:280357 11/56 (20%)
zf-TRAF 200..250 CDD:280357 5/49 (10%)
Smc <255..>372 CDD:224117 28/121 (23%)
MATH_TRAF3 382..564 CDD:239746 2/19 (11%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D918518at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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