DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and rnf41

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_002934542.1	Gene:	rnf41 / 100489964	XenbaseID:	XB-GENE-943148	Length:	317	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	183/315 - (58%)
Similarity:	253/315 - (80%)	Gaps:	0/315 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGYDVNRFQGEVDEELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQPTCPVDRNSLTTANL 65
            |||||:||||:|||:|.|||||||||:|:||..||||||..||.:|.::|.||||||:.:|.|:|
Frog     1 MGYDVSRFQGDVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCPVDRSVVTVAHL 65

  Fly    66 RAVPRILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDIPKDELK 130
            |.||||:||:||:|.||||||.:|||.:::||...|||.:|.||||||..||:|||.::|||||.
Frog    66 RPVPRIMRNMLSKLQITCDNAVFGCTTIVRLDNLMSHLSDCEHNPKRPVTCEQGCGLEMPKDELP 130

  Fly   131 DHNCVRELRTLIVKQTEKMGELKSELTDQQLTINELKRELQLFKDFMRAMRVSNPAMRAIADQME 195
            :|||::.||:::.:|..::|||:....:.:..::|.||::||.|.:|||:|.:||.::.:.:.:|
Frog   131 NHNCIKHLRSVVQQQQIRIGELEKAAAESKHQLSEQKRDIQLLKAYMRAIRSANPNLQNLEETIE 195

  Fly   196 RDEVIRWSSTLPRARVTRWGGMISTPDDALQLMIKRALSESGCPPHILDSLMEFCHERRWPRGLS 260
            .:|::.|.::|..||||||||||||||..||.:|||:|.|||||..|::.|:|..|||.||:||:
Frog   196 YNEILEWVNSLQPARVTRWGGMISTPDAVLQAVIKRSLVESGCPASIVNELIENAHERNWPQGLA 260

  Fly   261 SLETRQTNRRIYDNYVCRRIPGKQAVLVLSCDNLHMTEDVMIDPGLVMIFAHGIE 315
            :|||||.|||.|:|||.:||||||||:|::|:|.||.||::::||||||||||:|
Frog   261 TLETRQMNRRYYENYVAKRIPGKQAVVVMACENQHMGEDMVLEPGLVMIFAHGVE 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	24/37 (65%)
		Sina	83..>157	CDD:302762	38/73 (52%)
		USP8_interact	137..315	CDD:286082	94/177 (53%)
rnf41	XP_002934542.1	mRING-HC-C3HC3D_Nrdp1	15..57	CDD:319548	27/41 (66%)
		modified RING-HC finger (C3HC3D-type)	18..56	CDD:319548	25/37 (68%)
		USP8_interact	137..315	CDD:370198	94/177 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2757
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4226
Inparanoid	1	1.050	364	1.000	Inparanoid score	I2127
OMA	1	1.010	-	-		QHG48595
OrthoDB	1	1.010	-	-		D422158at33208
OrthoFinder	1	1.000	-	-		FOG0007809
OrthoInspector	1	1.000	-	-		oto104944
Panther	1	1.100	-	-	LDO	PTHR15315
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5674
SonicParanoid	1	1.000	-	-		X5758
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110