DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment elgi and traf1

DIOPT Version :9

Sequence 1:	NP_001261904.1	Gene:	elgi / 39735	FlyBaseID:	FBgn0283649	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001121853.1	Gene:	traf1 / 100148503	ZFINID:	ZDB-GENE-071120-4	Length:	551	Species:	Danio rerio

Alignment Length:	311	Identity:	67/311 - (21%)
Similarity:	107/311 - (34%)	Gaps:	97/311 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EELTCPICSGVLEDPLQAVMCEHAFCRGCINEWLTRQ------PTCPVDRNSLTTANLRAVPR-- 70
            ::..|..|:.||....|.| |.|.:|..|:| ||.|.      ..|..:.:::.:......|.
Zfish    38 DKYLCSNCNNVLNKARQTV-CGHRYCLACVN-WLVRNNKDLVCTKCKGEDSNVESDTSVLTPNQF 100

  Fly    71 -----ILRNLLSRLSITCDNAPYGCTAVLKLDAYNSHLDECIHNPKRPFPCEKGCGFDIPKDELK 130
                 |.:.:|. |.:.|.|  .||.....|..:..|..:|.:   ...||..|||..:.:..|.
Zfish   101 FNDVAINKEILD-LKVHCAN--QGCPWRSTLKNFEDHQSQCEY---ALIPCNIGCGIMVQRKTLA 159

  Fly   131 DH-------------NCV-----RELRTLIVKQTEKMGELKSELTDQQ----LTINELKRE---- 169
            .|             :|.     |||:..:...:   |:.|:..||::    ...|..|:|
Zfish   160 THLESGCPNNKTACPSCTSVLTPRELQKHVCPSS---GDKKTAKTDKKQKNNQPANSKKKEPCIF 221

  Fly   170 -------------------------LQLFKDFMRAM-RVSNPAMRAIADQMERDEVI------RW 202
                                     |||..|..||: |..|.|    .:::.:|..:      ..
Zfish   222 SDVGCPFKGNPDKVKEHESCSHAGHLQLLLDVTRALQRTLNSA----TERVYQDSPVFLEPGPNG 282

  Fly   203 SSTLPRA--RVTRWGGMISTPDDALQL---MIKRALSESGCPPHILDSLME 248
            ||..|:|  .:...||.....|.|..|   .::.|..:.      ||:|.:
Zfish   283 SSLAPQADGDIETDGGDPGVSDKAFSLHDDQVELAAGQQ------LDALQQ 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
elgi	NP_001261904.1	RING	17..55	CDD:238093	15/43 (35%)
		Sina	83..>157	CDD:302762	20/91 (22%)
		USP8_interact	137..315	CDD:286082	32/157 (20%)
traf1	NP_001121853.1	zf-TRAF	134..188	CDD:280357	13/56 (23%)
		TRAF_BIRC3_bd	320..375	CDD:293278	3/14 (21%)
		MATH_TRAF1	402..548	CDD:239748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0297
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D918518at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820