Protein Alignment Pka-C3 and SCH9

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_012075.1
• Gene: SCH9 / 856612
• SGDID: S000001248
• Length: 824
• Species: Saccharomyces cerevisiae
• Alignment Length: 583
• Identity: 170/583 - (29%)
• Similarity: 278/583 - (47%)
• Gaps: 80/583 - (13%)

  Fly    39 DHDSASGLRAGLATPT------QRGKATGDNG-TTGTPARTIGKPQARIATAMSTATCARFCTPL 96
            |:.|:|.....|.:.|      ||..|....| .|..|.   ||.:..|..|....|.::...|.
Yeast   144 DNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPR---GKLEVTIIEARDLVTRSKDSQPY 205

  Fly    97 SSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSES 161
            ...|..|:..::.|..|...:       :||:   |:::|.:......:..:|..::.:.||...
Yeast   206 VVCTFESSEFISNGPESLGAI-------NNNN---NNNNNNQHNQNQHINNNNENTNPDAASQHH 260

  Fly   162 SDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDA 226
            ::....:.|:....:|..:..|....||||......:.|    :..|......:.:.|..||...
Yeast   261 NNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCS----SVTDPSKRSSNSSSGSSNGPKN 321

  Fly   227 D--------------------------DATHD-------------------SSESIEEDDGNETD 246
            |                          ||.||                   |............|
Yeast   322 DSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVID 386

  Fly   247 DEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVI 311
            :....|...:.:..||.|  |.|...|:::::.:|.||||:|...:.:.:::..|||:|:...::
Yeast   387 EVVSGDILIKWTYKQTKK--RHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIV 449

  Fly   312 RLKQIEHVKNERNIL---REIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQT 373
            :..:|.|...|||||   .....||::.|::|.:..::||::.||:.|||||.:|:..|:|:...
Yeast   450 KKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDR 514

  Fly   374 SNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAK-KLRDRTWTLCGTPEYIA 437
            :.||.||:|.|||:||...||||||||||:|::.:|::.:.|||.:| .|:|||.|.|||.||:|
Yeast   515 AKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLA 579

  Fly   438 PE-IIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERH-MDPIAKDLI 500
            || ::...|:.|.||:|:|||||:||..|:.||:.|....:|:||..||:::.|. :....:..:
Yeast   580 PELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFV 644

  Fly   501 KKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPE 563
            |.||..:...|||.:.:|. :::.|.:|..::|..:..||:.||..|.:..:.||.|||  ||
Yeast   645 KGLLNRNPKHRLGAIDDGR-ELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFD--PE 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	115/296 (39%)
SCH9	NP_012075.1	YPK1_N_like	181..407	CDD:212165	42/244 (17%)
		STKc_Sck1_like	418..738	CDD:270738	116/290 (40%)