Protein Alignment Pka-C3 and CBK1

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_014238.3
• Gene: CBK1 / 855561
• SGDID: S000005105
• Length: 756
• Species: Saccharomyces cerevisiae
• Alignment Length: 703
• Identity: 182/703 - (25%)
• Similarity: 291/703 - (41%)
• Gaps: 186/703 - (26%)

  Fly    28 GLYSSWKLICGDHDS--------ASGLRAGL---------ATPTQRGKATGDNGTTGTPARTIGK 75
            |..|::....|.|.|        ...|.:|.         |||.........|....||..::|
Yeast    52 GFSSNYMKEQGSHQSLQEHLQRETGNLGSGFTDVPALNYPATPPPHNNYAASNQMINTPPPSMG- 115

  Fly    76 PQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTM-----TSAYKIPSNNSTTANDSS 135
                               .|......|.|.:..||||||..     ...|.|.|..:...|.||
Yeast   116 -------------------GLYRHNNNSQSMVQNGNGSGNAQLPQLSPGQYSIESEYNQNLNGSS 161

  Fly   136 NTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPA--TNSRSSSTATTTTT 198
            ::......:..||||..||.:.|.:|...|:   .|::..|.||:...|  .|||..........
Yeast   162 SSSPFHQPQTLRSNGSYSSGLRSVKSFQRLQ---QEQENVQVQQQLSQAQQQNSRQQQQQLQYQQ 223

  Fly   199 SSADHDN----DVDEEDEEDDENE--------GEGNG---------RDAD---DATHDSSESIEE 239
            .......    .:.::.::..:.:        |..||         |..|   ..|.|.:.:::.
Yeast   224 QQQQQQQQQHMQIQQQQQQQQQQQQSQSPVQSGFNNGTISNYMYFERRPDLLTKGTQDKAAAVKL 288

  Fly   240 DDGN----------ETDDEEDDDE--------SEESSSVQTAKGVRK-----------YHLDDYQ 275
            ...|          |.::...:.|        |||..|.|.:...:|           ..|:|:.
Yeast   289 KIENFYQSSVKYAIERNERRVELETELTSHNWSEERKSRQLSSLGKKESQFLRLRRTRLSLEDFH 353

  Fly   276 IIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWS 340
            .:|.:|.|.||.|.|.:.:.:.|..|||.|..:|:.:..|:.|||.||::|.....|:|:||.:|
Yeast   354 TVKVIGKGAFGEVRLVQKKDTGKIYAMKTLLKSEMYKKDQLAHVKAERDVLAGSDSPWVVSLYYS 418

  Fly   341 TKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLI 405
            .:|...||:|.:::.||:|.|.|.....||...:.||.||.:.|:|.:|.|..::||:||:|:||
Yeast   419 FQDAQYLYLIMEFLPGGDLMTMLIRWQLFTEDVTRFYMAECILAIETIHKLGFIHRDIKPDNILI 483

  Fly   406 NRDGHLKITDFG------------FAKKL------------------------------------ 422
            :..||:|::|||            :.|||
Yeast   484 DIRGHIKLSDFGLSTGFHKTHDSNYYKKLLQQDEATNGISKPGTYNANTTDTANKRQTMVVDSIS 548

  Fly   423 -------RDRTW---------TLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYD 471
                   :.:||         :..|||:||||||...:|:.:..|||:||.::||.|:|:|||..
Yeast   549 LTMSNRQQIQTWRKSRRLMAYSTVGTPDYIAPEIFLYQGYGQECDWWSLGAIMYECLIGWPPFCS 613

  Fly   472 EQPFGIYEKILSGKIEWER--------HMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWF 528
            |.|...|.||::    :|:        |:...|:|||::||.: ..:|||. ..|||::|.|.:|
Yeast   614 ETPQETYRKIMN----FEQTLQFPDDIHISYEAEDLIRRLLTH-ADQRLGR-HGGADEIKSHPFF 672

  Fly   529 KHLNWNDVYSKKLKPPILPDVHHDGDTKNF-----DDYPEKDWKPAKAVDQRD 576
            :.::||.:  ::::.|.:|.:....||:.|     ::.|:.. ..|:|..||:
Yeast   673 RGVDWNTI--RQVEAPYIPKLSSITDTRFFPTDELENVPDSP-AMAQAAKQRE 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	114/367 (31%)
CBK1	NP_014238.3	MobB_CBK1	269..341	CDD:439268	13/71 (18%)
		STKc_NDR_like_fungal	350..748	CDD:270778	119/382 (31%)