Protein Alignment Pka-C3 and PKC1

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_009445.2
• Gene: PKC1 / 852169
• SGDID: S000000201
• Length: 1151
• Species: Saccharomyces cerevisiae
• Alignment Length: 585
• Identity: 157/585 - (26%)
• Similarity: 278/585 - (47%)
• Gaps: 123/585 - (21%)

  Fly    71 RTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSS 135
            ||:  |.|::.:::.||          :|:..|.|||..              .:|.........
Yeast   557 RTV--PSAQLGSSIGTA----------NGSDLSPSKLAE--------------RANAPLPPQPRK 595

  Fly   136 NTETTFTFKLGR------------------SNGRSSSNVASSESSDPLE-SDYSEEDPE--QEQQ 179
            :.:|....|:||                  ::||...|....|:...|. ::.:::..|  ..::
Yeast   596 HDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEK 660

  Fly   180 RPDPATNSRS-----SSTATTTTTSSAD-----------------------------HDNDVDEE 210
            ..||.:|.||     .|...:.|..|.|                             .|.:||..
Yeast   661 TLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHI 725

  Fly   211 DEEDDEN---EGEGNGRDAD---DATHD------SSES--IEEDDGNE----------------- 244
            |.|..:.   |.:.:.|:||   |:||.      :||:  ||:|..::
Yeast   726 DLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHAS 790

  Fly   245 -TDDEEDDDESEESSSVQTAKGV---RKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKIL 305
             |.|::...:|:.|:|.:..|..   ||..||::.::|.:|.|.||:|.|.:.:.:::.||:|:|
Yeast   791 RTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVL 855

  Fly   306 AMTEVIRLKQIEHVKNERNIL---REIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAG 367
            ....:|:...||..:.|:.:.   .:.:|||:.:|..|.:.::.:|...:::.||:|..:::|.
Yeast   856 KKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ- 919

  Fly   368 KFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKK---LRDRTWTL 429
            :.:.:.:.|||||::.||:|.|...::|||||.||:|:..:||:||.|:|..|.   ..:||.|.
Yeast   920 RLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTF 984

  Fly   430 CGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDP 494
            |||||::||||::.:.:.|||||||.|||:|:||:...||..:....::..||:.:..:...|..
Yeast   985 CGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAG 1049

  Fly   495 IAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFD 559
            ....:.:.||..|..||||.....||:|....:|:::|::|:.:.::|||.:|::....||..|:
Yeast  1050 EIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFE 1114

  Fly   560  559
            Yeast  1115  1114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	100/294 (34%)
PKC1	NP_009445.2	HR1_PKC-like_1_fungi	1..72	CDD:212011
		HR1_PKC-like_2_fungi	110..181	CDD:212010
		C2_fungal_Pkc1p	211..319	CDD:176071
		C1_ScPKC1-like_rpt1	413..464	CDD:410372
		C1_ScPKC1-like_rpt2	478..536	CDD:410373
		STKc_PKC	828..1145	CDD:270722	99/288 (34%)