DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C3 and prkacaa

DIOPT Version :9

Sequence 1:	NP_730083.2	Gene:	Pka-C3 / 39733	FlyBaseID:	FBgn0000489	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_021326630.1	Gene:	prkacaa / 564064	ZFINID:	ZDB-GENE-050114-6	Length:	389	Species:	Danio rerio

Alignment Length:	347	Identity:	176/347 - (50%)
Similarity:	242/347 - (69%)	Gaps:	13/347 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 GEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTG 283
            |.|.|.:......|..|.:.:       .:||..:..|:.:..||.      ||.::.:||:|||
Zfish    40 GSGGGVEGPTLLVDVKEFLAK-------AKEDFLKKWENPAQNTAS------LDHFERLKTLGTG 91

  Fly   284 TFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLY 348
            :||||.|.:.:.|.::.|||||...:|::||||||..||:.||:.:..||::.||.|.||::|||
Zfish    92 SFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLY 156

  Fly   349 MIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKI 413
            |:.:||.|||:|::||..|:|:...:.||||:||...||||||.::|||||||||||::.|::::
Zfish   157 MVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQV 221

  Fly   414 TDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIY 478
            |||||||:::.|||||||||||:|||||.|||:||||||||||||||||..|||||:.:||..||
Zfish   222 TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIY 286

  Fly   479 EKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKP 543
            |||:|||:.:..|.....|||::.||..|.|||.||:|||.:|:|.|:||...:|..:|.||::.
Zfish   287 EKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEA 351

  Fly   544 PILPDVHHDGDTKNFDDYPEKD 565
            |.:|.....|||.|||||.|::
Zfish   352 PFIPKCKGPGDTSNFDDYDEEE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	PTZ00263	262..583	CDD:140289	168/304 (55%)
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	164/290 (57%)
prkacaa	XP_021326630.1	STKc_PKA	80..369	CDD:271111	162/288 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820