Protein Alignment Pka-C3 and PRKACG

DIOPT Version :9

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_002723.2
• Gene: PRKACG / 5568
• HGNCID: 9382
• Length: 351
• Species: Homo sapiens
• Alignment Length: 352
• Identity: 162/352 - (46%)
• Similarity: 245/352 - (69%)
• Gaps: 12/352 - (3%)

  Fly   242 GNETDDEEDDDESEESSSVQTAKGVRKYH----------LDDYQIIKTVGTGTFGRVCLCRDRIS 296
            ||....::.:.|...:..:..|:|...|.          .|.::.::|:|.|:||||.|.|.:.:
Human     2 GNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQET 66

  Fly   297 EKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFT 361
            ..:.|||||...:|:::||:||:.||:.||:.|..||::.|::|.||:|.||::.:||.|||:|:
Human    67 GGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFS 131

  Fly   362 YLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRT 426
            .|:..|:|:...:.||||::|.|::|||||.:::||||||||||::.|:|::|||||||:::.||
Human   132 RLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRT 196

  Fly   427 WTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERH 491
            |||||||||:|||||.|||:||||||||||||||||.||:||||.:||..|||||:||::.:...
Human   197 WTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSK 261

  Fly   492 MDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTK 556
            :....|.|::.||..|.|||.||::||..|:|.|:||...:|..:|.||::.|.:|.....||..
Human   262 LSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDAS 326

  Fly   557 NFDDYPEKDWKPAKAVDQRDLQYFNDF 583
            |||||.|::.:  .:::::..:.|::|
Human   327 NFDDYEEEELR--ISINEKCAKEFSEF 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	PTZ00263	262..583	CDD:140289	158/330 (48%)
		STKc_PRKX_like	272..563	CDD:270763	153/290 (53%)
PRKACG	NP_002723.2	PTZ00426	36..351	CDD:173616	155/316 (49%)
		STKc_PKA	42..331	CDD:271111	151/288 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0616
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100326
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.720