Protein Alignment Pka-C3 and Pkn

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001097237.1
• Gene: Pkn / 35950
• FlyBaseID: FBgn0020621
• Length: 1501
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 145/549 - (26%)
• Similarity: 267/549 - (48%)
• Gaps: 96/549 - (17%)

  Fly    61 GDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPS 125
            |.|...||          |:.::.|::...|||..:    .....||..|        |:.:..:
  Fly  1016 GSNENLGT----------RLHSSHSSSAGDRFCVEV----IPQLGKLYVG--------SSQQQYA 1058

  Fly   126 NNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPATN---- 186
            ..|:.......|.|.:           .::.|:.....|..:...|:.|.|:|  |..|..
  Fly  1059 QQSSPIIQEPATPTIY-----------GNSAAAGAPQFPQPAQRQEKQPPQQQ--PIYANQYELN 1110

  Fly   187 -SRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEED 250
             :::::.|:..:.||:...|. :::.::...|...|.
  Fly  1111 VAKAAAAASVYSPSSSTTSNS-NQQQQQQRRNVARGL---------------------------- 1146

  Fly   251 DDESEESSSVQTAKGVRK------YHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTE 309
              :..||..::|.:..::      ..:|:::::..:|.|.||:|.|.:.|.:.:|.|:|.|...:
  Fly  1147 --QYRESGGLETGRAGKQPPNAGMLSMDNFRLLSVLGRGHFGKVILSQLRSNNQYYAIKALKKGD 1209

  Fly   310 VIRLKQIEHVKNERNIL---REIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTS 371
            :|...::|.:.:|:.|.   ..:||||:::|....:.:.::..:.:|..||:|..:: :...|..
  Fly  1210 IIARDEVESLLSEKRIFEVANAMRHPFLVNLYSCFQTEQHVCFVMEYAAGGDLMMHI-HTDVFLE 1273

  Fly   372 QTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKK---LRDRTWTLCGTP 433
            ..:.||||.:|..|:|||..:|:|||||.:|||::.:|::||.|||..|:   ..|||.|.||||
  Fly  1274 PRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTP 1338

  Fly   434 EYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKD 498
            |::|||::....:.:|||||.|||||:|||||..||..:....:::.|::.::.:.|.:...|..
  Fly  1339 EFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLEAIA 1403

  Fly   499 LIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDD--- 560
            ::::||..:..:|||:.:..|:|||:..:|:.:.|:|:..:|:|||.:|.::|..|..|||:
  Fly  1404 VMRRLLRKNPERRLGSSERDAEDVKKQAFFRSIVWDDLLLRKVKPPFVPTINHLEDVSNFDEEFT 1468

  Fly   561 ------YPEKDWKPAKAVDQRDLQYFNDF 583
                  .|.|:  |....::..| .|.||
  Fly  1469 SEKAQLTPPKE--PRHLTEEEQL-LFQDF 1494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	105/305 (34%)
Pkn	NP_001097237.1	HR1_PKN_1	131..194	CDD:212012
		HR1_PKN_2	243..309	CDD:212013
		HR1_PKN_3	340..414	CDD:212015
		C2	530..611	CDD:472691
		STKc_PKN	1174..1499	CDD:270741	111/325 (34%)