DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pka-C3 and Prkaca

DIOPT Version :9

Sequence 1:NP_730083.2 Gene:Pka-C3 / 39733 FlyBaseID:FBgn0000489 Length:583 Species:Drosophila melanogaster
Sequence 2:NP_001094392.1 Gene:Prkaca / 25636 RGDID:3389 Length:351 Species:Rattus norvegicus


Alignment Length:363 Identity:181/363 - (49%)
Similarity:253/363 - (69%) Gaps:13/363 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   221 GNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTF 285
            ||...|...:  ..||::|.....   :||..:..|:.|..||:      ||.:..|||:|||:|
  Rat     2 GNAAAAKKGS--EQESVKEFLAKA---KEDFLKKWETPSQNTAQ------LDHFDRIKTLGTGSF 55

  Fly   286 GRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMI 350
            |||.|.:.:.|..:.|||||...:|::||||||..||:.||:.:..||::.||:|.||:|||||:
  Rat    56 GRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120

  Fly   351 FDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITD 415
            .:||.|||:|::||..|:|:...:.||||:||...||||||.::|||||||||||::.|::::||
  Rat   121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTD 185

  Fly   416 FGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEK 480
            |||||:::.|||||||||||:|||||.|||:||||||||||||||||..|||||:.:||..||||
  Rat   186 FGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250

  Fly   481 ILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPI 545
            |:|||:.:..|.....|||::.||..|.|||.||:|||.:|:|.|:||...:|..:|.:|::.|.
  Rat   251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPF 315

  Fly   546 LPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF 583
            :|.....|||.|||||.|::.:  .:::::..:.|.:|
  Rat   316 IPKFKGPGDTSNFDDYEEEEIR--VSINEKCGKEFTEF 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Pka-C3NP_730083.2 PTZ00263 262..583 CDD:140289 170/320 (53%)
STKc_PRKX_like 272..563 CDD:270763 165/290 (57%)
PrkacaNP_001094392.1 PTZ00426 16..334 CDD:173616 173/326 (53%)
STKc_PKA 42..331 CDD:271111 163/288 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0616
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D277423at33208
OrthoFinder 1 1.000 - - FOG0000539
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100326
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.720

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