Protein Alignment Pka-C3 and STK38L

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_055815.1
• Gene: STK38L / 23012
• HGNCID: 17848
• Length: 464
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 123/395 - (31%)
• Similarity: 206/395 - (52%)
• Gaps: 72/395 - (18%)

  Fly   234 SESIEEDDGNETDDE------EDDDESEESSSVQTAKGVRK-----------YHLDDYQIIKTVG 281
            |..|.:.:..||..:      |::..::|...::.::..||           ..|||::.:|.:|
Human    33 SNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIG 97

  Fly   282 TGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSN 346
            .|.||.|.|.:.:.:....|||||..::::..:|:.|::.||:||.|....:|:.:.:|.:|..|
Human    98 RGAFGEVRLVQKKDTGHIYAMKILRKSDMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRN 162

  Fly   347 LYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHL 411
            ||:|.:::.||::.|.|......|.:.:.||.:|.|.|::.:|.|..::||:||:|||::..||:
Human   163 LYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHV 227

  Fly   412 KITDFGFA-----------------------------KKLRDRTW---------TLCGTPEYIAP 438
            |::|||..                             .|.:..||         :..|||:||||
Human   228 KLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAP 292

  Fly   439 EIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHM-----DPI--- 495
            |:....|:||..|||:|||::||||:|||||..|.|...|.|:::    |:..:     .||
Human   293 EVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYRKVMN----WKETLVFPPEVPISEK 353

  Fly   496 AKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDD 560
            |||||.:..: |...|:||  :|.:::|.|.:|:.::|..:..:....||  ::....||.||||
Human   354 AKDLILRFCI-DSENRIGN--SGVEEIKGHPFFEGVDWEHIRERPAAIPI--EIKSIDDTSNFDD 413

  Fly   561 YPEKD 565
            :||.|
Human   414 FPESD 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	111/336 (33%)
STK38L	NP_055815.1	MobB_NDR_LATS-like	12..86	CDD:459252	8/52 (15%)
		S100B binding. /evidence=ECO:0000250	63..88		2/24 (8%)
		STKc_NDR2	87..452	CDD:270776	115/341 (34%)