Protein Alignment Pka-C3 and STK32A

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001274669.1
• Gene: STK32A / 202374
• HGNCID: 28317
• Length: 407
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 94/309 - (30%)
• Similarity: 171/309 - (55%)
• Gaps: 32/309 - (10%)

  Fly   252 DESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQI 316
            ||:|:            .:.|.::|::.:|.|:||:||:.:...::|..|||.:...:.:...::
Human    13 DENED------------VNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEV 65

  Fly   317 EHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEI 381
            .:|..|..|::.:.|||:::|.:|.:|:.:::|:.|.:.||:|..:|:....|..:|...:..|:
Human    66 RNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICEL 130

  Fly   382 VSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRT--WTLCGTPEYIAPEIIQSK 444
            |.||:||.:.:|::||:||:|:|::..||:.||||..|..|...|  .|:.||..|:|||:..|:
Human   131 VMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSR 195

  Fly   445 ---GHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYE-------KILSGKIEWERHMDPIAKDL 499
               |::.|||||:|||..||:|.|..|::........|       .:::....|.:.|    ..|
Human   196 KGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEM----VSL 256

  Fly   500 IKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPD 548
            :||||..:..:|...:    .||:...:...:||:.|:.|:|.|..:|:
Human   257 LKKLLEPNPDQRFSQL----SDVQNFPYMNDINWDAVFQKRLIPGFIPN 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	91/289 (31%)
STK32A	NP_001274669.1	STKc_Yank1	22..281	CDD:270730	83/266 (31%)