Protein Alignment Pka-C3 and Prkaca

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_032880.1
• Gene: Prkaca / 18747
• MGIID: 97592
• Length: 351
• Species: Mus musculus
• Alignment Length: 363
• Identity: 181/363 - (49%)
• Similarity: 253/363 - (69%)
• Gaps: 13/363 - (3%)

  Fly   221 GNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTF 285
            ||...|...:  ..||::|.....   :||..:..|:.|..||:      ||.:..|||:|||:|
Mouse     2 GNAAAAKKGS--EQESVKEFLAKA---KEDFLKKWETPSQNTAQ------LDQFDRIKTLGTGSF 55

  Fly   286 GRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMI 350
            |||.|.:.:.|..:.|||||...:|::||||||..||:.||:.:..||::.||:|.||:|||||:
Mouse    56 GRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120

  Fly   351 FDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITD 415
            .:||.|||:|::||..|:|:...:.||||:||...||||||.::|||||||||||::.|::::||
Mouse   121 MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTD 185

  Fly   416 FGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEK 480
            |||||:::.|||||||||||:|||||.|||:||||||||||||||||..|||||:.:||..||||
Mouse   186 FGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250

  Fly   481 ILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPI 545
            |:|||:.:..|.....|||::.||..|.|||.||:|||.:|:|.|:||...:|..:|.:|::.|.
Mouse   251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPF 315

  Fly   546 LPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF 583
            :|.....|||.|||||.|::.:  .:::::..:.|.:|
Mouse   316 IPKFKGPGDTSNFDDYEEEEIR--VSINEKCGKEFTEF 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	165/290 (57%)
Prkaca	NP_032880.1	STKc_PKA	42..331	CDD:271111	163/288 (57%)