Protein Alignment Pka-C3 and Sgk3

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001362972.1
• Gene: Sgk3 / 171498
• RGDID: 620242
• Length: 496
• Species: Rattus norvegicus
• Alignment Length: 328
• Identity: 127/328 - (38%)
• Similarity: 198/328 - (60%)
• Gaps: 12/328 - (3%)

  Fly   243 NETDDEEDDDESEESSSVQTAKGVR-----KYHL--DDYQIIKTVGTGTFGRVCLCRDRISEKYC 300
            :::|..||:||........|::.:.     ..|.  .|:..:|.:|.|:||:|.|.:.::..|:.
  Rat   124 HQSDPSEDEDERSTPKPHSTSRNINLGPTGNPHAKPSDFDFLKVIGKGSFGKVLLAKRKLDGKFY 188

  Fly   301 AMKILAMTEVIRLKQIEHVKNERNI-LREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLR 364
            |:|:|....|:..|:.:|:..|||: |:.::|||::.|.:|.:....||.:.|:|.|||||.:|:
  Rat   189 AVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQ 253

  Fly   365 NAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKK---LRDRT 426
            ....|....:.||||||.|||.||||::||||||||||:|::..||:.:||||..|:   :.|.|
  Rat   254 RERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTT 318

  Fly   427 WTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERH 491
            .|.||||||:|||:|:.:.::..||||.||.::||||.|.||||......:|:.||...:.....
  Rat   319 TTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPG 383

  Fly   492 MDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTK 556
            :...|..::::||..:|..||| .|....:::.|.:|:.|:|.|:..||:.||..|:|....|.:
  Rat   384 VSLTAWSILEELLEKNRQNRLG-AKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIR 447

  Fly   557 NFD 559
            |||
  Rat   448 NFD 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	120/292 (41%)
Sgk3	NP_001362972.1	PX_CISK	12..120	CDD:132780
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..157		6/32 (19%)
		STKc_SGK3	165..490	CDD:270755	119/287 (41%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		2/9 (22%)