Protein Alignment Pka-C3 and LOC1276766

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_061497361.1
• Gene: LOC1276766 / 1276766
• VectorBaseID: AGAMI1_006872
• Length: 1756
• Species: Anopheles gambiae
• Alignment Length: 754
• Identity: 196/754 - (25%)
• Similarity: 304/754 - (40%)
• Gaps: 236/754 - (31%)

  Fly    54 TQRGKATGDNGTTGTPART--IGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLT-TGNGSGN 115
            |:.|...|..|..|..|..  |...:.|:|...:..|......|.|||..||..|.. ...|.|.
Mosquito     7 TRAGAGVGGGGGGGVAAINPGISISRGRVAATRTHETRLYAEEPSSSGAGGSRRKAAQAATGGGG 71

  Fly   116 TMTSAYKIPSNNSTTANDS-SNTETTFTFKLGRSNG-------------------------RSSS 154
            .|.::.:|.......|..: |:..:.:..:.|.|..                         |...
Mosquito    72 RMAASRRIEELYQRAAESTMSSLLSGYGMRKGLSESIPPATLIEHVVADATIGMQHLGKRQRQQR 136

  Fly   155 NVA----SSESSDPLESD--YSEEDPEQEQQR--------------------------------- 180
            .:|    :.|:...::||  ..|:|.:|:|||
Mosquito   137 QLAGYRQAREAHMIIDSDGTSGEDDDDQQQQRRADEQQEEEEDRYLEALDGIRLDEEEDEEEGDD 201

  Fly   181 -PDPATNSRSSS--------------TATTTTTSSADHDNDVDEEDEEDDENEGEGNG------- 223
             .:..|...|||              .....||||:.|..:.||||||:.|.:|.|..
Mosquito   202 EEEVQTVVNSSSVRWSRRQRKGGRAVAGACDTTSSSVHGEEDDEEDEEEQEEDGAGQALEGEEED 266

  Fly   224 ------------------------------------------------------------RDADD 228
                                                                        .:|:|
Mosquito   267 NEYEEQEELEGGMQGDEEEEYEEAADGDEHEQQQYLEDEEQEEVDEEQDQEYEEQDQEYDEEAED 331

  Fly   229 ATHDSSE-------SIEEDDGNETDDEEDD----------DESEESSSVQTAKGVR--------- 267
            ...:..|       ::|||:..|.:|::||          ||.:|...:|.|:...
Mosquito   332 VEDEEEEEEDGQHQAVEEDEEEEEEDDDDDVIIQDEVIDVDEHDEKRQLQHARHKEQQQQQQQNG 396

  Fly   268 ---------------------------------------KYHLDDYQIIKTVGTGTFGRVCLCR- 292
                                                   |..|:|::::|.:|||.:|.|.|.:
Mosquito   397 TDASKRQDSPVTQTQADIDELEMIKISAINTKVQLNDRDKVSLEDFELLKVLGTGAYGTVYLVQK 461

  Fly   293 ----DRISEKYCAMKILAMTEV-IRLKQIEHVKNERNILREIRH-PFVISLEWSTKDDSNLYMIF 351
                |:  :|..|||:|....| ::.|..||.:.||.:|..|:. ||::::.::.:.||.||:|.
Mosquito   462 LTGVDK--DKIYAMKVLKKGIVSLKKKTAEHTRTERQVLEAIQEAPFLVTMHYAFQTDSKLYLIL 524

  Fly   352 DYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDF 416
            |||.||||||.|.|...|.......|.|||:.|:|:||.|.|||||:|.||:|::.|||:.:|||
Mosquito   525 DYVIGGELFTLLCNRMHFDEPAVQIYIAEIIVAIEHLHKLGIVYRDIKLENILVDVDGHIVLTDF 589

  Fly   417 GFAKKL---RDRTWTLCGTPEYIAPEIIQ--SKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFG 476
            |.:::|   .:|..:.|||.||:||||::  .:||:.|||||::|||.:|:|.|..||..:|. .
Mosquito   590 GLSRELVYENERAHSFCGTVEYMAPEILKPTQQGHDSAVDWWSVGVLTFELLTGASPFTADQN-E 653

  Fly   477 IYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKL 541
            |..:|...:.....::.|.|.|.|::|||.|..:|||:.|..|.::|.|.:.:.:||:.:..|::
Mosquito   654 IARRITETEAIIPENLSPEATDFIRRLLVKDPKRRLGSGKGDASELKSHPFLRSINWSRLVRKQI 718

  Fly   542 KPPILPDVHHDGDTKNF------DDYPEKDWKPAKAVDQ 574
            :.|..|...:|.||:||      .:..||..:|.|..|:
Mosquito   719 EAPYPPLAENDRDTRNFSSEFTKQEVTEKPCEPPKNADR 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	120/308 (39%)
LOC1276766	XP_061497361.1	None