Protein Alignment Pka-C3 and Cit

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_006530193.1
• Gene: Cit / 12704
• MGIID: 105313
• Length: 2123
• Species: Mus musculus
• Alignment Length: 315
• Identity: 99/315 - (31%)
• Similarity: 167/315 - (53%)
• Gaps: 36/315 - (11%)

  Fly   273 DYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISL 337
            |:::...||.|.|..|.:.|::.:....||||:....::..:|:...:.|||||.....|::..|
Mouse    96 DFEVRSLVGCGHFAEVQVVREKATGDVYAMKIMKKKALLAQEQVSFFEEERNILSRSTSPWIPQL 160

  Fly   338 EWSTKDDSNLYMIFDYVCGGELFTYL-RNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPE 401
            :::.:|.:|||::.:|..||:|.:.| |...:.......||.||::.|:..:|.:..|:||:|||
Mouse   161 QYAFQDKNNLYLVMEYQPGGDLLSLLNRYEDQLDESMIQFYLAELILAVHSVHQMGYVHRDIKPE 225

  Fly   402 NLLINRDGHLKITDFGFAKKLRDRTWTL---CGTPEYIAPEIIQSKGHNKA------VDWWALGV 457
            |:||:|.||:|:.|||.|.|:.......   .|||:|:|||::.....::.      .|||::||
Mouse   226 NILIDRTGHIKLVDFGSAAKMNSNKVDAKLPIGTPDYMAPEVLTVMNEDRRGTYGLDCDWWSVGV 290

  Fly   458 LIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHM----DPIAK----DLIKKLLV--NDRTKRL 512
            :.|||:.|..||.:    |...:..:..:.::|.:    ||...    ||::.||.  .:|.|..
Mouse   291 VAYEMVYGKTPFTE----GTSARTFNNIMNFQRFLKFPDDPKVSSELLDLLQSLLCVQKERLKFE 351

  Fly   513 GNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKD-W 566
            |        :..|.:|...:||::  :...||.:|.:..|.||.|||: |||: |
Mouse   352 G--------LCCHPFFARTDWNNI--RNSPPPFVPTLKSDDDTSNFDE-PEKNSW 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	95/309 (31%)
Cit	XP_006530193.1	STKc_CRIK	96..421	CDD:270752	99/315 (31%)
		CwlO1	441..>597	CDD:443091
		SMC_prok_B	530..1273	CDD:274008
		CwlO1	1153..>1430	CDD:443091
		CRIK	1438..1493	CDD:410364
		PH	1523..1642	CDD:459697
		CNH	1687..1983	CDD:214481