Protein Alignment Pka-C3 and Akt1

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: NP_001159366.1
• Gene: Akt1 / 11651
• MGIID: 87986
• Length: 488
• Species: Mus musculus
• Alignment Length: 409
• Identity: 144/409 - (35%)
• Similarity: 224/409 - (54%)
• Gaps: 26/409 - (6%)

  Fly   171 EEDPEQEQQRPDPATNSRSSSTATTTT---------------TSSADHDNDVDEEDEEDDENEGE 220
            :|.|:...||..|..|...:......|               |:..:....|:..:|.::
Mouse    39 KERPQDVDQRESPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREE----- 98

  Fly   221 GNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTF 285
              ...|.....|..:..||:..:.......|:...|...|..||...:..:::::.:|.:|.|||
Mouse    99 --WATAIQTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTF 161

  Fly   286 GRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMI 350
            |:|.|.:::.:.:|.|||||....::...::.|...|..:|:..||||:.:|::|.:....|..:
Mouse   162 GKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFV 226

  Fly   351 FDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHS-LQIVYRDLKPENLLINRDGHLKIT 414
            .:|..|||||.:|.....|:...:.||.|||||||:|||| ..:||||||.|||::::|||:|||
Mouse   227 MEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKIT 291

  Fly   415 DFGFAKK-LRDRTW--TLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFG 476
            |||..|: ::|...  |.||||||:|||:::...:.:|||||.|||::|||:.|..|||::....
Mouse   292 DFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEK 356

  Fly   477 IYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKL 541
            ::|.||..:|.:.|.:.|.||.|:..||..|.|:|||.....|.::.:||:|.::.|.|||.|||
Mouse   357 LFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKKL 421

  Fly   542 KPPILPDVHHDGDTKNFDD 560
            .||..|.|..:.||:.||:
Mouse   422 SPPFKPQVTSETDTRYFDE 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	125/293 (43%)
Akt1	NP_001159366.1	PH_PKB	4..111	CDD:269947	12/78 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..137		4/22 (18%)
		STKc_PKB	154..466	CDD:270723	125/287 (44%)