DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-C3 and prkx

DIOPT Version :9

Sequence 1:	NP_730083.2	Gene:	Pka-C3 / 39733	FlyBaseID:	FBgn0000489	Length:	583	Species:	Drosophila melanogaster
Sequence 2:	XP_002941045.1	Gene:	prkx / 100494406	XenbaseID:	XB-GENE-6046135	Length:	369	Species:	Xenopus tropicalis

Alignment Length:	317	Identity:	198/317 - (62%)
Similarity:	264/317 - (83%)	Gaps:	0/317 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 RKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRH 331
            ::|.|||:..:.||||||||||.|.::::.::|.|:|::::.:||||||.:||.||:::|:|:.|
Frog    53 QQYKLDDFDTVATVGTGTFGRVHLVKEKMGKQYFALKVMSIPDVIRLKQEQHVHNEKSVLKEVNH 117

  Fly   332 PFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYR 396
            ||::.|.|::.||..|||:.:||.|||||:||||.|:|.:.|..||:.||:.|:|||||.:||||
Frog   118 PFLVKLFWTSHDDRFLYMLMEYVPGGELFSYLRNMGRFNNSTGLFYSTEIICAIEYLHSKEIVYR 182

  Fly   397 DLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYE 461
            ||||||:|::::||:|:|||||||||.||||||||||||:|||:||||||.:||||||||:||:|
Frog   183 DLKPENILLDKEGHIKLTDFGFAKKLSDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFE 247

  Fly   462 MLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHR 526
            ||.|:|||:|:.|||||:|||:|||::.||:|...|||||||||.|||:||||||||||||||||
Frog   248 MLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDLYVKDLIKKLLVVDRTRRLGNMKNGADDVKRHR 312

  Fly   527 WFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF 583
            ||:.::|:.|..:||||||:|.|.|:|||.||:.|||.||..|..|..:||:.||.|
Frog   313 WFRSIDWDTVPPRKLKPPIIPKVTHEGDTSNFEAYPEDDWNKAPPVPPKDLEMFNSF 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	PTZ00263	262..583	CDD:140289	197/315 (63%)
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	185/290 (64%)
prkx	XP_002941045.1	STKc_PRKX_like	58..349	CDD:270763	185/290 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	380	1.000	Domainoid score	I836
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55868
Inparanoid	1	1.050	454	1.000	Inparanoid score	I1553
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D277423at33208
OrthoFinder	1	1.000	-	-		FOG0000539
OrthoInspector	1	1.000	-	-		oto103820
Panther	1	1.100	-	-	LDO	PTHR24353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4097
SonicParanoid	1	1.000	-	-		X4144
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100