Protein Alignment Pka-C3 and prkg2

DIOPT Version :10

• Sequence 1: NP_730083.2
• Gene: Pka-C3 / 39733
• FlyBaseID: FBgn0000489
• Length: 583
• Species: Drosophila melanogaster
• Sequence 2: XP_021331649.2
• Gene: prkg2 / 100125912
• ZFINID: ZDB-GENE-060531-80
• Length: 769
• Species: Danio rerio
• Alignment Length: 536
• Identity: 171/536 - (31%)
• Similarity: 260/536 - (48%)
• Gaps: 86/536 - (16%)

  Fly   116 TMTSAYKIPSNNSTTANDSS------NTETTFTFKLGRSNGRSSSNVAS------SESSDPLESD 168
            |.|::.|..||..|.|.|..      ........:..|:..||.|.:||      ::..|.||.:
Zfish   248 TRTASVKAASNVKTWALDREVFHNIMRMTAEARHEQYRNFLRSVSLLASLPGDKLTKIVDCLEVE 312

  Fly   169 YSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGN--GRDA---DD 228
            |..:.....::..:..|....::.....|.|:.||      |:.:.....|:|:  |..|   ||
Zfish   313 YYNKGDYIIREGEEGNTFYIIANGKIKVTQSTQDH------EEPQIINTLGKGDYFGEKALISDD 371

  Fly   229 ATHDSSESIEEDDGNE--TDDEEDDDESEESSSVQTAKGVRKYHLDDY----------------- 274
            ..  |:..|.|:||.|  ..|.|     ..|.:|.|...::|| |..|
Zfish   372 VR--SANIIAEEDGVECLVIDRE-----TFSQTVGTFDELKKY-LQSYVDSLARDDKKRNAKRSG 428

  Fly   275 --------------------------------QIIKTVGTGTFGRVCLCRDRISEKYCAMKILAM 307
                                            :.|.|:|.|.||||.|.:.:......|:|.:..
Zfish   429 SCTPPNTPVSHDMIELKERESSFASTIPFTCLEAIATLGVGGFGRVELVKLKNENVTFALKCIKK 493

  Fly   308 TEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQ 372
            ..::..:|.||:.:||.||.|...||::.:..:.||:..:||:.:...|||:::.||:.|.|...
Zfish   494 RHIVDNRQEEHIYSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEY 558

  Fly   373 TSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLR--DRTWTLCGTPEY 435
            |:.|....:..|.||||:..|:|||||||||:::.||::|:.||||||||:  .||||.||||||
Zfish   559 TAKFCVGCVTEAFEYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEY 623

  Fly   436 IAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSG--KIEWERHMDPIAKD 498
            :|||||.:|||..:||:|:||:||:|:|.|.|||.......||..||.|  |:::.:.:.....|
Zfish   624 VAPEIILNKGHGLSVDFWSLGILIFELLTGSPPFTGSDQMIIYTFILKGIEKMDFPKKITKRPGD 688

  Fly   499 LIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPE 563
            ||:||...:.::||||:|||..|:|:||||...:|:.:.::.|..|:..:|....|...||.||.
Zfish   689 LIRKLCRQNPSERLGNLKNGITDIKKHRWFTGFSWSGLKARNLISPLKREVKGPTDHSYFDSYPP 753

  Fly   564 KDWKPAKAVDQRDLQY 579
            ::..|...:...|..:
Zfish   754 EEEIPPDEMSGWDTDF 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-C3	NP_730083.2	STKc_PRKX_like	272..563	CDD:270763	124/343 (36%)
prkg2	XP_021331649.2	None