Protein Alignment sff and TSSK1B

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_114417.1
• Gene: TSSK1B / 83942
• HGNCID: 14968
• Length: 367
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 121/402 - (30%)
• Similarity: 189/402 - (47%)
• Gaps: 76/402 - (18%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMK-VEREIAIMKLIDHPHVLGLS 81
            |.|...||:|....||......:...||||||:|:|.....|.| :.|||.|:.:::|..::...
Human    12 YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTY 76

  Fly    82 DVYENKK-YLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPEN 145
            :::|... .:|:::|....|:|.:.:..:|.|...||||.|.|:..|:.:||...:.|||||.:|
Human    77 EIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDN 141

  Fly   146 LLLDEKNNIKIADFGMAS---LQPAGSML--ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL 205
            ||||:..|||::||..:.   ...:|.|.  :|.||||.||.|||::|..|..:..|:||.||||
Human   142 LLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVIL 206

  Fly   206 YALLVGALPFDDDNLRQLL--EKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPW 268
            |.::.|::|:||.|::::|  :|..|..|.....:..:|:.|:..|::.:.:|||.:.||..|.|
Human   207 YIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCW 271

  Fly   269 VTAGGKGELELELPMMEVVQTHVIPTATAVDPDV-LNAICSLGCFKEKEKLIQELLSSSHNTEKV 332
            :....:|                       .|.| :|        ||.|        ||..||.:
Human   272 MQPKARG-----------------------SPSVAIN--------KEGE--------SSRGTEPL 297

  Fly   333 IYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGT--------------NAPS 383
                      ..|....|.:.|.|...|.:|  .|:.:.:| :..||              :.||
Human   298 ----------WTPEPGSDKKSATKLEPEGEA--QPQAQPET-KPEGTAMQMSRQSEILGFPSKPS 349

  Fly   384 YGQISEGSPLTP 395
            ..:..||.|..|
Human   350 TMETEEGPPQQP 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	93/259 (36%)
		UBA_BRSK	298..350	CDD:270525	11/52 (21%)
TSSK1B	NP_114417.1	STKc_TSSK1_2-like	10..272	CDD:271067	93/259 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..367		27/138 (20%)