DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sff and KIN10

DIOPT Version :9

Sequence 1:	NP_648814.3	Gene:	sff / 39732	FlyBaseID:	FBgn0036544	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_850488.1	Gene:	KIN10 / 821259	AraportID:	AT3G01090	Length:	535	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	177/491 - (36%)
Similarity:	266/491 - (54%)	Gaps:	49/491 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVL-MKVEREIAIMKLIDHPHVLGLS 81
            |:|.:|||.|..|.||:..|.:.|.||||||:||.|:....: .||.|||.|::|..|||::.|.
plant    42 YKLGRTLGIGSFGRVKIAEHALTGHKVAIKILNRRKIKNMEMEEKVRREIKILRLFMHPHIIRLY 106

  Fly    82 DVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 146
            :|.|....:||::|:|:.||||||:|:||||...|||.||:||||.:::||.:.:.|||||||||
plant   107 EVIETPTDIYLVMEYVNSGELFDYIVEKGRLQEDEARNFFQQIISGVEYCHRNMVVHRDLKPENL 171

  Fly   147 LLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            |||.|.|:||||||::::...|..|:||||||:||.||||.|:.|.|.:.|||||||||||||.|
plant   172 LLDSKCNVKIADFGLSNIMRDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCG 236

  Fly   212 ALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            .|||||:|:..|.:|:|.|::.:|..:.|..:.|:..|:.|:|.:|:|:.||.:|||..|
plant   237 TLPFDDENIPNLFKKIKGGIYTLPSHLSPGARDLIPRMLVVDPMKRVTIPEIRQHPWFQA----- 296

  Fly   277 LELELP-MMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLER 340
               .|| .:.|.....:..|..:|.::|..:.::|.  ::..||:.|.:.:.|...|.|:|:|:.
plant   297 ---HLPRYLAVPPPDTVQQAKKIDEEILQEVINMGF--DRNHLIESLRNRTQNDGTVTYYLILDN 356

  Fly   341 KRRRPA------LEDDDEIAQKSRSELDAVDPPRKRL-DTCRINGTNAPSYGQISEGSPLTPRRQ 398
            :.|..:      .::..|...:.........|...|| ......|....|...:.       |:.
plant   357 RFRASSGYLGAEFQETMEGTPRMHPAESVASPVSHRLPGLMEYQGVGLRSQYPVE-------RKW 414

  Fly   399 AFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTRHSTY 463
            |...:|    |.|.|...|.|..:::..:.     |...:.....:...:  |:|.|.|...::.
plant   415 ALGLQS----RAHPREIMTEVLKALQDLNV-----CWKKIGHYNMKCRWV--PNSSADGMLSNSM 468

  Fly   464 GDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRI 499
            .|.:..|..||:           ||.: ..|:.|.:
plant   469 HDNNYFGDESSI-----------IENE-AAVKSPNV 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	132/251 (53%)
		S_TKc	18..269	CDD:214567	132/251 (53%)
		UBA_BRSK	298..350	CDD:270525	12/57 (21%)
KIN10	NP_850488.1	STKc_AMPK_alpha	39..294	CDD:270981	132/251 (53%)
		S_TKc	42..294	CDD:214567	132/251 (53%)
		UBA_SnRK1_plant	316..356	CDD:270520	11/41 (27%)
		AMPKA_C	411..532	CDD:213378	21/112 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100252
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810