Protein Alignment sff and Prkaa2

DIOPT Version :9

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_076481.1
• Gene: Prkaa2 / 78975
• RGDID: 620893
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 583
• Identity: 188/583 - (32%)
• Similarity: 276/583 - (47%)
• Gaps: 123/583 - (21%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVL 78
            :|.|.|..|||.|..|.||:|.|.:.|.|||:||:||:|: |..|:.|::|||..:||..|||::
  Rat    13 IGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHII 77

  Fly    79 GLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKP 143
            .|..|.......::::|:|||||||||:.|.||:...|||:.|:||:||:|:||.|.:.||||||
  Rat    78 KLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLFQQILSAVDYCHRHMVVHRDLKP 142

  Fly   144 ENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYAL 208
            ||:|||.:.|.||||||::::...|..|.||||||:||.||||.|..|.|.:.|:||||||||||
  Rat   143 ENVLLDAQMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYAL 207

  Fly   209 LVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGG 273
            |.|.|||||:::..|.:|::.|||:||.::.....:||..|::|:|.:|.|:.:|..|.|
  Rat   208 LCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSIATLLMHMLQVDPLKRATIKDIREHEW----- 267

  Fly   274 KGELELELPMMEVVQTHVIP-----TATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEK-- 331
               .:.:||      :::.|     .|..:|.:.:..:|..  |:..|..:...|.|....::
  Rat   268 ---FKQDLP------SYLFPEDPSYDANVIDDEAVKEVCEK--FECTESEVMNSLYSGDPQDQLA 321

  Fly   332 VIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPR 396
            |.|.|:::.:|         .:.|.|...|.:..|....:|...::         |..|  |.|
  Rat   322 VAYHLIIDNRR---------IMNQASEFYLASSPPTGSFMDDMAMH---------IPPG--LKP- 365

  Fly   397 RQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTRHS 461
                          |..|.|              |...:||.:.....|...::|.|.|......
  Rat   366 --------------HPERMP--------------PLIADSPKARCPLDALNTTKPKSLAVKKAKW 402

  Fly   462 TYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERR------------------------ 502
            ..|.|.:|..:..::.......|...|..||.....|:.|:
  Rat   403 HLGIRSQSKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLL 467

  Fly   503 ------DSLRQERGGGS-------------PRDRGDCGIP-----PGSPGGNSSGST--SASP 539
                  |.:.::|.|.|             ||...|....     .||..|:.:|||  ||||
  Rat   468 DFKSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSVDSSTAENHSLSGSLTGSLTGSTLSSASP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	128/253 (51%)
		S_TKc	18..269	CDD:214567	127/251 (51%)
		UBA_BRSK	298..350	CDD:270525	10/53 (19%)
Prkaa2	NP_076481.1	STKc_AMPK_alpha	13..268	CDD:270981	129/262 (49%)
		S_TKc	16..268	CDD:214567	128/259 (49%)
		UBA_AID_AAPK2	285..349	CDD:270587	15/74 (20%)
		AIS. /evidence=ECO:0000250	291..376		22/135 (16%)
		AMPKA2_C	395..550	CDD:213385	27/136 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	478..520		9/41 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100252
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810