Protein Alignment sff and mark2

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_012808991.1
• Gene: mark2 / 594939
• XenbaseID: XB-GENE-876451
• Length: 792
• Species: Xenopus tropicalis
• Alignment Length: 824
• Identity: 250/824 - (30%)
• Similarity: 379/824 - (45%)
• Gaps: 169/824 - (20%)

  Fly     8 TAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLI 72
            ||:....:|.|||.||:|||....|||..|.:.||:||:|||::.:|:.|.|.|:.||:.|||::
 Frog    54 TADEQPHIGNYRLLKTIGKGNFAKVKLARHVLTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVL 118

  Fly    73 DHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 137
            :||:::.|.:|.|.:|.|||::|:.||||:|||||..||:..||||..||||:||:.:||...|.
 Frog   119 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKLIV 183

  Fly   138 HRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 202
            |||||.||||||...||||||||.::....|:.|:|.||||.||.||:.:|:||||.:.||||.|
 Frog   184 HRDLKAENLLLDSDMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 248

  Fly   203 VILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHP 267
            ||||.|:.|:||||..||::|.|:|.||.:.||.::..||::||:..:.:||.:|.||.:|.|..
 Frog   249 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPAKRGTLEQIMRDR 313

  Fly   268 WVTAGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKV 332
            |:..|.: |.||: |.:|       |.....||.....:.::|  ..:|::...|::..:| |.:
 Frog   314 WMNVGHE-EDELK-PYVE-------PIPDYKDPKRTELMITMG--YTREEISDSLVNQKYN-EVM 366

  Fly   333 IYFLLLERKRRRPALEDDDEIAQKSRSELD-----------------AVDPPRKRL-DTCRINGT 379
            ..:|||..|...   .|:|.:..|.|...|                 :.:|.::|| |.......
 Frog   367 ATYLLLGYKSSE---TDNDNLTLKPRPPPDVTNSIAPSPAHKVQRSVSANPKQRRLSDQAGPAIP 428

  Fly   380 NAPSYGQISEGSPLTPRR----QAFNFRSYSSTR---------NHQRRSPTTVTSSVRSSSYHSP 431
            |:.||.:.::.:....||    :....:|.|:.|         :.::.:||..|:||.|:..:..
 Frog   429 NSNSYSKKTQSNNAENRRSEDDKESGRKSSSTVRVPPSPLSGLDRKKTTPTPSTNSVLSTGTNRS 493

  Fly   432 TRCNSPM--------SSAQQQANAISRPSSPAAGTRHSTYGDRDRSGHHSSVSRTPSHSSQ--KS 486
            .  ||||        .|.|...::.|.|.|.|:.........|.|. |..|:| |..|.|:  .|
 Frog   494 R--NSPMLDRASLVPGSVQNGKDSFSTPGSRASTASAPATSARIRQ-HQKSMS-TSVHPSKPAPS 554

  Fly   487 IEGDV-----------VVVREPRIERRDSLRQE-----RGGGS-----------PRDRGDCG--- 521
            ::|:.           |.|..|......|...|     ||..|           .||:.:.|
 Frog   555 LDGNCEVQRPSTAPQRVPVASPSAHNISSAATERTNFPRGVSSRSTFHAGQVRQARDQQNLGFGS 619

  Fly   522 IPPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPCN 586
            :.|.||.|||.|...|:.|:..:..|               ..|..|.|......:|       |
 Frog   620 VSPASPSGNSQGRRGATGSIFSKFTS---------------KFVRRNLSFRFPRRNP-------N 662

  Fly   587 TPGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADEVHLT-----------PESSPELTKRSWFGN 640
            .|.|                       |.:|.:...|||           .:|.|...:.:|  :
 Frog   663 EPEG-----------------------KDRVESTRPHLTVLDKEKDKEDHRDSKPRSLRFTW--S 702

  Fly   641 LITTEKDETFTILVKGKPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGNGPVMFQRHVK 705
            :.||...|...::.:           |...|......|...........:...|:     ..:|:
 Frog   703 MKTTSSMEPNEMMSE-----------IRKVLDANNCQHESQEKYMLLCVHGTPGH-----DNYVQ 751

  Fly   706 FQVDISAICKQGDIADMLFALTFTLLSGNIRRFRRICEHIQSQV 749
            ::::   :||...::  |..:.|..:||....|:.|...|.:::
 Frog   752 WEME---VCKLPRLS--LNGVRFKRISGTSIAFKNIASKIANEL 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	133/252 (53%)
		UBA_BRSK	298..350	CDD:270525	11/51 (22%)
mark2	XP_012808991.1	STKc_MARK	63..315	CDD:270974	132/251 (53%)
		UBA_MARK2	333..374	CDD:270589	10/43 (23%)
		MARK2_C	693..791	CDD:213386	19/121 (16%)