Protein Alignment sff and hunk

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_021329890.1
• Gene: hunk / 564235
• ZFINID: ZDB-GENE-050309-240
• Length: 644
• Species: Danio rerio
• Alignment Length: 582
• Identity: 170/582 - (29%)
• Similarity: 261/582 - (44%)
• Gaps: 101/582 - (17%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSES--VLMKVEREIAIMKLIDHPHV 77
            |..|.:.:.||:|...:|:.|:|.:.|:|||:|||:::|..:.  ||..:.||..|.::|.|||:
Zfish    46 VSDYLIGRKLGEGSFAIVREGLHVITGEKVAVKIIDKKKAKKDSYVLKNLRREGNIQQMIRHPHI 110

  Fly    78 LGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLK 142
            ..|.|:.|.:...||::|...||.|.:|:.:..||..:||.|:.||::.|::..|...:.|||||
Zfish   111 AQLLDIMETENRFYLVMELCPGGNLMNYIYENKRLEEREANKYVRQLVMAVEHLHRAGVVHRDLK 175

  Fly   143 PENLLLDEKNNIKIADFGMASLQPAGSM-----LETSCGSPHYACPEVIRGEKYDGRKADVWSCG 202
            .||||||:.:|:|:.|||:::  .||.:     ..|.||||.||.||::..:|| |.|.||||.|
Zfish   176 IENLLLDDHDNLKLIDFGLSN--SAGILGYSDPFSTQCGSPAYAAPELLSRKKY-GPKVDVWSIG 237

  Fly   203 VILYALLVGALPF--DDDNLRQLLEK-VKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEIN 264
            |.:||:|.|.|||  :..:|..|.:| :.:.:..:|..:..|.:.||..::|..||.|..:.::.
Zfish   238 VNMYAMLTGTLPFTVEPFSLNALYKKMINKEMNPLPSNISSDAKHLLEVLLEPKPDLRPNIHQVL 302

  Fly   265 RHPWVTAGGK---GELELELPMMEV---VQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELL 323
            .|||:..|..   ..|...:.:.|:   |..|:..........||||                ||
Zfish   303 SHPWLQLGNPHTGAPLFNRIHIKEINKSVLCHMTEKMGYSHSAVLNA----------------LL 351

  Fly   324 SSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSELD-AVDPPR-------KRLDTCRINGTN 380
            ::..:|...:|| ||..|..|.:.|...:   |.|..|| ..:.|.       |.:||..|....
Zfish   352 TNKASTTLAVYF-LLNNKMNRLSKECKQD---KQRQNLDNRENKPEIIQTQCLKYIDTVTIPPKE 412

  Fly   381 APSYGQISEGSPLTPRRQAF--------NFR-SYSST---------------RNHQRRSPTTVTS 421
            .|.|  ::.|.....::|..        .|: :||..               |.|....|...|.
Zfish   413 TPVY--LASGKDPIKKKQKTGLLKAVKGGFKDAYSGNGGCITSSSLEYLKIHRLHPTPEPILPTP 475

  Fly   422 SVRSSSYHSPTRCNS------------PMSS--AQQQANAISRPS--SPAAGTRHSTYGDRDRSG 470
            ..:     .|.:|:|            |.||  :....:....||  ||.:.....|.|......
Zfish   476 ETQ-----PPEQCSSKDPPKAEKIPARPPSSLGSHSWTSESKEPSKDSPPSPWYKLTNGALSPPK 535

  Fly   471 HHSSVSRTPSHSSQKSIEGDVVVVREPRIERR----DSLRQERGGGSP-RDRGDCGIPPGSP 527
            |.|:.....|:..:.:|....|:|..|:..:.    ||:......||| ..||  ...|.||
Zfish   536 HVSAFQPESSYLKKATIPSPPVLVVRPQPRKNAPSSDSMSSSDSNGSPLSSRG--SEEPQSP 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	100/262 (38%)
		UBA_BRSK	298..350	CDD:270525	14/51 (27%)
hunk	XP_021329890.1	Protein Kinases, catalytic domain	46..307	CDD:473864	101/263 (38%)