Protein Alignment sff and mark2a

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_009293774.1
• Gene: mark2a / 562231
• ZFINID: ZDB-GENE-030131-4145
• Length: 782
• Species: Danio rerio
• Alignment Length: 837
• Identity: 250/837 - (29%)
• Similarity: 379/837 - (45%)
• Gaps: 185/837 - (22%)

  Fly     8 TAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLI 72
            ||:....:|.|||.||:|||....|||..|.:.||:||:|||::.:|:.|.|.|:.||:.||||:
Zfish    34 TADEQPHIGCYRLLKTIGKGNFAKVKLAKHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKLL 98

  Fly    73 DHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 137
            :||:::.|.:|.|.:|.|||::|:.||||:|||||..||:..||||..||||:||:.:||...|.
Zfish    99 NHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIV 163

  Fly   138 HRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCG 202
            |||||.||||||...||||||||.::....|:.|:|.||||.||.||:.:|:||||.:.||||.|
Zfish   164 HRDLKAENLLLDADMNIKIADFGFSNEFTLGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLG 228

  Fly   203 VILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTL-AEINRH 266
            ||||.|:.|:||||..||::|.|:|.||.:.||.::..||::||:..:.:||.:|.:| .:|.:.
Zfish   229 VILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPTKRGSLEQQIMKD 293

  Fly   267 PWVTAGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEK---------EKLIQEL 322
            .|:..|.:.| ||: |.:|....:..|..|...|.      |.|.:|..         :::...|
Zfish   294 RWMNVGHEDE-ELK-PYIEPQPDYKDPKRTGQHPS------SAGGWKRDIMIRMGYSLDEIQDSL 350

  Fly   323 LSSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSY-GQ 386
            ::..:|.....|.||..|.      .:.||::.|:|...|..            |...:||: ||
Zfish   351 INQKYNDVMATYLLLDYRN------SELDELSIKARPGTDIT------------NNAQSPSHKGQ 397

  Fly   387 ISEGSPLTPRRQAFNFRSYSSTR------------------------NHQRRSPTTVTSSVRSSS 427
            .|. |.|..||.. :..|.||.|                        ...:::||..|:|:.||.
Zfish   398 RST-SNLKSRRST-DQSSVSSKRPQGDSKHIGSSGSSSKVPPSPLISGDHKKTPTPSTNSILSSG 460

  Fly   428 YHSPTRCNSPMS-----SAQQQANAISRPSSPAA-GTRHSTYGDRDRSGHHSSVSRTPSHSSQKS 486
              :....|||::     ..|...:::..|.|.|: .:..:......|:.||.|:| |.:|.|...
Zfish   461 --TGRSRNSPITERATLGVQNGKDSLHTPGSRASTASAAAVLAASSRTRHHKSLS-TSAHPSPPD 522

  Fly   487 IEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGSTSASPSVHHRAN-SGPT 550
            :..           .|.|...:|.            |..||...:...:|.:    .|.| |...
Zfish   523 LHA-----------HRPSTANQRA------------PVVSPSAQNINISSMA----DRTNFSRGV 560

  Fly   551 IAISMFH--------DPDSNSVVNPNGSPMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFLGS 607
            .:.|.||        |..:::..:|:.||.:::.:     |....||        |.|.:.|  :
Zfish   561 TSRSTFHAGQQRATRDQQASAYNDPSASPSLSHGN-----SQVRRPG--------TGIFSKF--T 610

  Fly   608 PRFHRRKMQVSADEVHLTPESSP-------ELTKRSWFGNLITTEKDETFTILVKGKPIATVKAH 665
            .:|.||.:...      .|..||       |.::..    |.|.:|.|..|   :|.|....|
Zfish   611 SKFVRRNLSFR------FPRRSPYEGEGRDEASRPM----LSTADKMEKGT---QGHPSDENK-- 660

  Fly   666 LIHAFLSMAELSHSVVS--------PTSFRVEYKRNGNG---PVMFQRHVKFQVDISA------- 712
              .:|.|.:..|.:..|        |.|.|..:......   |....:.::..:|.::
Zfish   661 --DSFSSSSPASSTPSSTQASKDTKPRSLRFTWSMKTTSSMEPNEMMKEIRKVLDSNSCEYELRE 723

  Fly   713 ----ICKQGDIAD----------------MLFALTFTLLSGNIRRFRRICEHIQSQV 749
                :|..|:.|.                .|..:.|..:||....|:.|...|.:::
Zfish   724 RFMLLCMSGNPAHDDFVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANEL 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	132/253 (52%)
		UBA_BRSK	298..350	CDD:270525	10/60 (17%)
mark2a	XP_009293774.1	STKc_MARK	44..296	CDD:270974	131/251 (52%)
		UBA_MARK2	314..367	CDD:270589	11/58 (19%)
		MARK2_C	683..781	CDD:213386	15/98 (15%)