Protein Alignment sff and nuak1b

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_689990.3
• Gene: nuak1b / 561496
• ZFINID: ZDB-GENE-131120-18
• Length: 613
• Species: Danio rerio
• Alignment Length: 638
• Identity: 184/638 - (28%)
• Similarity: 287/638 - (44%)
• Gaps: 150/638 - (23%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLS 81
            |.|.:|||:|..|.|:..:....|::||||.|.:||: .|..::.:.|||.||..:.|||::.:.
Zfish    48 YELLETLGRGTYGKVRKAIERHSGREVAIKSIRKEKIKDEQDMVHIRREIEIMSSLRHPHIISIY 112

  Fly    82 DVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 146
            :|:|||..:.:::|:.|.|||:||:.::.|||.:|.|.|||||:||:.:||.:.:.|||||.||:
Zfish   113 EVFENKDKIVIVMEYASKGELYDYISERRRLTERETRHFFRQIVSAVHYCHKNGVVHRDLKLENV 177

  Fly   147 LLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            ||||..||||||||:::|.....:|:|.||||.||.||::.|..|.|.:.|.|:.||:||.|:.|
Zfish   178 LLDENCNIKIADFGLSNLYHKDKLLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYG 242

  Fly   212 ALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            ::|||..:.:.|:.::..|.:..|. ...|.:.|:|.|:.|||:||.|:.:|..|.||..|.|
Zfish   243 SMPFDGGDHKNLIRQISNGEYREPS-QSSDARGLIRWMLMVNPERRATVEDIANHWWVNWGWK-- 304

  Fly   277 LELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEK---LIQELLSSSHNTE----KVIY 334
                                       |::|.  |..:::.   ::..|:...:.||    |.|.
Zfish   305 ---------------------------NSVCD--CESQRDNGSPMLARLIDWQNRTEPRPTKAIR 340

  Fly   335 ---FLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPR 396
               |||:.::.::...|:|..::..:..:...:..|:..|.|.......:||..:|..|:. ||.
Zfish   341 SEPFLLVRQRPKKSKKENDVGVSHCNGEDSLGLKRPKGILKTRTSEEQRSPSLEEIESGAG-TPE 404

  Fly   397 RQA-----------FNFRSYSST--------RNHQRRSPTTVTSSVRSSSYHSPTRCNS------ 436
            :::           .|..|.|.:        :|:|:|         .|..|.||.|..|
Zfish   405 KESGPDGEDGDEEQGNSPSKSVSILPKKGILKNNQQR---------ESGYYSSPERSESSDLLSG 460

  Fly   437 ---PMSSAQQQANAISRPSSPAAGTRHSTYGDRDRSG-------HHSSVSRTPSHSSQKSIEGDV 491
               |::::.....|:.|........::|||......|       ..|.:||:.|..|.
Zfish   461 NITPLAASSPPKRAVGRKGILKRNGKYSTYSGAPPLGVLGEPAPSDSGLSRSQSRPSS------- 518

  Fly   492 VVVRE---------------------PRIERRDSLRQERGGGSPRDRGDCGIPP----------- 524
             :|||                     |.|  |..|..|........:|....||
Zfish   519 -IVREDSDTITNSSFCSTEWPPPRTRPNI--RSCLSAENLLQLANFKGLQAAPPMHSGKFNRDAQ 580

  Fly   525 GSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSS 577
            ||||.|||                    .|:..|.|..:.|......:.||.|
Zfish   581 GSPGDNSS--------------------FSLLGDLDDMTQVYQQALDISNNLS 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	109/251 (43%)
		UBA_BRSK	298..350	CDD:270525	12/61 (20%)
nuak1b	XP_689990.3	None