DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sff and pimr109

DIOPT Version :9

Sequence 1:	NP_648814.3	Gene:	sff / 39732	FlyBaseID:	FBgn0036544	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_001038385.1	Gene:	pimr109 / 560132	ZFINID:	ZDB-GENE-030131-6182	Length:	465	Species:	Danio rerio

Alignment Length:	289	Identity:	79/289 - (27%)
Similarity:	129/289 - (44%)	Gaps:	29/289 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KENNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVE---- 63
            ||..:...|.|   .|.:...|.||..|.|..|.....|.:||:|:.:.:|   ..|:.|:
Zfish   191 KETQIIEINSQ---GYEIGAELDKGGCGTVYEGSRLEDGLQVAVKVSDFKK---KQLISVDGFDE 249

  Fly    64 ---REIAIMKLIDH----PHVLGLSDVYENKKYLYLILEH-VSGGELFDYLVKKGRLTPKE-ARK 119
               .|||:..|.:.    ..::.|.|......:.:::||. :....|||:..:...:.|:: .||
Zfish   250 PLPLEIALHFLANKGPKVKEIIELLDWKVEADHYFMVLERPIPCVSLFDFQNEHRGIIPEDKLRK 314

  Fly   120 FFRQIISALDFCHSHSICHRDLKPENLLLD-EKNNIKIADFGMASLQPAGSMLETSCGSPHYACP 183
            ...|.|.|...|....:.|||:|.||||:: :...:|:.|||...|. ...:.:|..|:..:|.|
Zfish   315 IMLQTIIAAQTCCQRGVFHRDIKLENLLINPDTLEVKLIDFGCGDLL-TEDIYKTFRGTREFAPP 378

  Fly   184 EVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIP-HFVPPDCQSLLR 247
            |.....:|.|..|.|||.||:|:.|:....|       :.|:..|....::| :.:..:|.....
Zfish   379 EFWMIGRYRGEPATVWSLGVVLFVLIFKRFP-------EKLDIPKMNNKNMPINGLSKECCDFFH 436

  Fly   248 GMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            |.:::|...||.|.::|.|.|.....|.|
Zfish   437 GCLQLNQMDRLDLQKLNSHEWFKMEDKEE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	72/267 (27%)
		S_TKc	18..269	CDD:214567	72/265 (27%)
		UBA_BRSK	298..350	CDD:270525
pimr109	NP_001038385.1	Pkinase	203..458	CDD:278497	72/265 (27%)
pimr109	NP_001038385.1	PKc_like	203..458	CDD:304357	72/265 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000