Protein Alignment sff and PIM1

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001230115.1
• Gene: PIM1 / 5292
• HGNCID: 8986
• Length: 404
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 90/287 - (31%)
• Similarity: 149/287 - (51%)
• Gaps: 33/287 - (11%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLM----KVEREIAIMKLID--HPH 76
            |::...||.|..|.|..|:.......||||.:.::::|:...:    :|..|:.::|.:.  ...
Human   129 YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSG 193

  Fly    77 VLGLSDVYENKKYLYLILEHVSG-GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRD 140
            |:.|.|.:|......||||.... .:|||::.::|.|..:.||.||.|::.|:..||:..:.|||
Human   194 VIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRD 258

  Fly   141 LKPENLLLD-EKNNIKIADFGMASLQPAGSMLETSC-----GSPHYACPEVIRGEKYDGRKADVW 199
            :|.||:|:| .:..:|:.|||      :|::|:.:.     |:..|:.||.||..:|.||.|.||
Human   259 IKDENILIDLNRGELKLIDFG------SGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVW 317

  Fly   200 SCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEIN 264
            |.|::||.::.|.:||:.|      |::.||.......|..:||.|:|..:.:.|..|.|..||.
Human   318 SLGILLYDMVCGDIPFEHD------EEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQ 376

  Fly   265 RHPWVTAGGKGELELELPMMEVVQTHV 291
            .|||:.       ::.|| .|..:.|:
Human   377 NHPWMQ-------DVLLP-QETAEIHL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	85/263 (32%)
		UBA_BRSK	298..350	CDD:270525
PIM1	NP_001230115.1	STKc_PIM1	128..381	CDD:271002	85/263 (32%)