Protein Alignment sff and AMPKalpha

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_477313.1
• Gene: AMPKalpha / 43904
• FlyBaseID: FBgn0023169
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 594
• Identity: 194/594 - (32%)
• Similarity: 288/594 - (48%)
• Gaps: 118/594 - (19%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVL 78
            :|.|.|..|||.|..|.||:|.|.:...|||:||:||:|: |..|:.|:.|||..:||..|||::
  Fly    25 IGHYLLGATLGTGTFGKVKIGEHQITRVKVAVKILNRQKIKSLDVVGKIRREIQNLKLFRHPHII 89

  Fly    79 GLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKP 143
            .|..|......:::|:|:|||||||||:||.|:|...:||:||:||||.:|:||.|.|.||||||
  Fly    90 KLYQVISTPSDIFMIMEYVSGGELFDYIVKHGKLQEHQARRFFQQIISGVDYCHRHMIVHRDLKP 154

  Fly   144 ENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYAL 208
            ||||||...::||||||::::...|..|.||||||:||.||||.|:.|.|.:.|:||||||||||
  Fly   155 ENLLLDHNMHVKIADFGLSNMMLDGEFLRTSCGSPNYAAPEVISGKLYAGPEVDIWSCGVILYAL 219

  Fly   209 LVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGG 273
            |.|.|||||:::..|..|:|.|:|.||.::.....:|:..|::|:|.:|..:.||.:|.|
  Fly   220 LCGTLPFDDEHVPTLFRKIKSGIFPIPEYLNKQVVNLVCQMLQVDPLKRANIEEIKKHEW----- 279

  Fly   274 KGELELELPMMEVVQTHVIPTATAVDPDVLNA-----ICSLGCFKEKEKLIQELLSSSHNTEKVI 333
               .:.:||      .::.|::...|.:|::.     :|:....||.|.....|....|:...:.
  Fly   280 ---FQKDLP------AYLFPSSIEQDSNVIDTYAVAEVCTKFGVKETEVHNSLLSGDPHDQLAIA 335

  Fly   334 YFLLLERKRRRPALEDDDEIAQKSRSELD----AVDPP--------------RKRLDTCRINGTN 380
            |.|:::.||    ..||   |....:|::    |..||              :..|.|..:.|..
  Fly   336 YHLIIDNKR----FADD---AANQINEINNFFVAGSPPPPPPPPVPQSSMDHQAPLATVTVGGGT 393

  Fly   381 APSYGQISEGSPL---TPRRQAFNFRSYSST---RNHQRR---------SPTTVTSS-------- 422
            :.|.|..:...|:   ||          |||   |.|..|         :.:..||.
  Fly   394 SASSGTATPVPPVAGGTP----------SSTIPIRPHPERIAPMRDRQLAMSVQTSGGGAFPEKT 448

  Fly   423 ------VRSSSYH----SPTRCNSPMSSAQQQANAIS---RPSSPAAGTRHSTYGDRDR-----S 469
                  ::.:.:|    |.::.|..|....:...|:|   :..:|        |..|.|     :
  Fly   449 ARGGTPIKRAKWHLGIRSQSKPNDIMLEVYRAMKALSYEWKIINP--------YHVRVRRQNVKT 505

  Fly   470 GHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGS 534
            |..|.:|........||...|...:....:|:.|.:..|            .:.|  |..:.||.
  Fly   506 GKFSKMSLQLYQVDAKSYLLDFKSLTNDEVEQGDDVIME------------SLTP--PPLSVSGV 556

  Fly   535 TSASPSVHH 543
            ....|:.||
  Fly   557 MPLQPTGHH 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	129/253 (51%)
		UBA_BRSK	298..350	CDD:270525	12/56 (21%)
AMPKalpha	NP_477313.1	STKc_AMPK_alpha	25..280	CDD:270981	130/262 (50%)
		UBA_AID_AMPKalpha	297..360	CDD:270521	15/69 (22%)
		AMPKA_C	457..580	CDD:213378	26/131 (20%)