Protein Alignment sff and Nuak

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001369005.1
• Gene: Nuak / 41256
• FlyBaseID: FBgn0262617
• Length: 2803
• Species: Drosophila melanogaster
• Alignment Length: 899
• Identity: 216/899 - (24%)
• Similarity: 356/899 - (39%)
• Gaps: 252/899 - (28%)

  Fly    22 KTLGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLSDVYE 85
            |.||:|..|.|:||::...|::||||.|.:.|: :|:.|:::.||:.||..:.||:::.:.:|:|
  Fly    74 KKLGQGTYGKVQLGINKETGQEVAIKTIKKCKIEAEADLVRIRREVQIMSSVHHPNIIHIYEVFE 138

  Fly    86 NKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDE 150
            |::.:.|::|..:||||:|||.::..||.:|||:.|||:.:|:.:||.|.|||||||.||:||||
  Fly   139 NREKMVLVMEFAAGGELYDYLSERKVLTEEEARRIFRQVATAVYYCHKHKICHRDLKLENILLDE 203

  Fly   151 KNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPF 215
            |.|.||||||::::.....:|.|.||||.||.||::.|..|.|.:.|.||.||:||.|:.|::||
  Fly   204 KGNAKIADFGLSNVFDDQRLLGTFCGSPLYASPEIVEGTPYQGPEVDCWSLGVLLYTLVYGSMPF 268

  Fly   216 DDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGELELE 280
            |..|.::|::::.:|.::.|. .|....:|:|.|:.|.|.:|.::.:|..|.||....      .
  Fly   269 DGSNFKRLVKQISQGDYYEPR-KPSRASTLIRDMLTVCPRKRASIEQICSHWWVNEND------N 326

  Fly   281 LPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERKRRRP 345
            :..:::.:.  :...|.|..|||.::                                     .|
  Fly   327 VSCLDLAED--LANQTPVRLDVLLSL-------------------------------------TP 352

  Fly   346 ALEDDDEIAQKSRSELDAVDP------PRKRLDTCRINGTNAPSYGQISEGSPLTPRRQAFNFRS 404
            |....|::...|.....|...      ||..            |.|.|.:..|  |..:|
  Fly   353 ATITADQLVVPSAEGAAAAKAAANERVPRSH------------SVGSIRDMGP--PNTEA----- 398

  Fly   405 YSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTRHSTYGDRDRS 469
                   :||....|.:...::...||||..:|..|..|    ..|...|...|.::       :
  Fly   399 -------ERRILDMVAAGGEAALMPSPTRTITPAQSPVQ----TKRKLQPTVSTENA-------A 445

  Fly   470 GHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGS 534
            |..:.....|::||       .|:.::                            |:|      .
  Fly   446 GTTAKKKEKPANSS-------FVISKD----------------------------GAP------L 469

  Fly   535 TSASPSV----------HHRANSGPTIAISMFHDPDSNSVVNPNG---SPMMNNSSPGMPGSPCN 586
            |.|.|::          ...||....:.:..:...|..:|    |   ..:|..::...|..|..
  Fly   470 TEAPPTIIEPQATLMEAETIANIPEEVPVPSYSQKDMQAV----GDICDLLMGTATTPAPAPPAP 530

  Fly   587 TP-GGQLWKTRL------------TNIKNSFLGSPRFHRRKMQVSADEVHLTPESS--------- 629
            || ..|..:.:|            |.:...|:..   |:     :||.|:...||:
  Fly   531 TPVARQPTRGKLDAVVETPEEKDATKVIKKFVNK---HK-----TADLVNAINESASKAAAPVSA 587

  Fly   630 ---PELTKRSWFGNLITTEKD----------ETFTILVKGKPIATVKAHLIHAFLSMAELSHSVV 681
               |...::....:..|..|.          ||........|:|.....      ...:||...|
  Fly   588 VAPPPFVRKCSLQDESTLNKFNAERRKSRILETAEKFQPPPPVAAAPPE------KPKKLSIPGV 646

  Fly   682 SPTSFRVEYKRNGNGPVMFQ----RHVKFQVDISAICKQGDIADMLFALTFTLLSGNIRRFRRIC 742
            |..||:.|:::....|...:    ..::.|..::|.......|:.|
  Fly   647 SVGSFKKEFEKKATNPPAAEGPTPGELRAQEQVAAAAAAAQEAETL------------------- 692

  Fly   743 EHIQSQVCSKRFPGPSSPPTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKSGN 807
                           |:||....|.|::..|.|..||:|..|...|:.:||.:
  Fly   693 ---------------STPPPSPVVAQSLEGSDSKNSVASISLDEARRSMENSI------------ 730

  Fly   808 GRRASTTNNNNANPVDIPGSPIAVRSNSETA-EHERNRELQSERQATTMSGSAI 860
             .......|.::..||...:.......||.| :.||.|:|::.|   .:.|:||
  Fly   731 -ALLLQAQNESSKEVDQLCAQTETIGVSEPATQQERERKLKNAR---AIIGNAI 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	106/247 (43%)
		UBA_BRSK	298..350	CDD:270525	6/51 (12%)
Nuak	NP_001369005.1	STKc_NUAK	68..321	CDD:270975	106/247 (43%)