Protein Alignment sff and Sik3

DIOPT Version :9

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Alignment Length: 1213
• Identity: 283/1213 - (23%)
• Similarity: 427/1213 - (35%)
• Gaps: 399/1213 - (32%)

  Fly     5 NNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIM 69
            :.::.:....||.|.||||:|||...:|||..:.|...|||||||::..|:|..|.|..|||||:
  Fly    28 SKISVDKLLRVGYYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAIL 92

  Fly    70 KLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSH 134
            |.:.|||:..|.:|.|::..:||:.|:...||:||:||..||:...||.:.|.|::||:.:||..
  Fly    93 KSLRHPHITRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRR 157

  Fly   135 SICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVW 199
            .:.|||||.||:|||:..|||:||||.::....|:.|:|.||||.||.|||.:|.:|||.|:|:|
  Fly   158 GVVHRDLKAENVLLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIW 222

  Fly   200 SCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEIN 264
            |.||:||||:.||||||...:.:|..:|..|.|.||.|:..:|:.|:|.|:.|.||||.|:.:|.
  Fly   223 SLGVVLYALVCGALPFDGKTILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQII 287

  Fly   265 RHPWVT---------------AGGKGELELEL------------PMME-VVQTHV--IPTATAVD 299
            :|.|::               :.|.|.:....            |.:: ||.||:  :|..||
  Fly   288 KHRWLSEWQSEMQEQERFGDMSPGSGTVSKSASTSSLGSASDSPPQLDSVVMTHMLQLPGLTA-- 350

  Fly   300 PDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFL----LLERKRRRPALEDDDEIAQKSRSE 360
                            :.:.|.:.....:....||.|    |.:|:|....|:....:|. |||.
  Fly   351 ----------------DMIAQSVHEQRFDNIYAIYNLLHDKLQQRRRENQRLQHHASLAY-SRSR 398

  Fly   361 --------LDAVDPPRKR-LDTCR-INGTNAPS----------------YGQI-------SEGSP 392
                    :|..:|.::. ||... ::..||.|                ||..       |...|
  Fly   399 KTSITTGVVDRSEPVKQESLDRLSPLSNANASSSALGFGWSDVAVDLEKYGDFELECLARSNDPP 463

  Fly   393 LTPRR---QAFNFRSYSSTRNHQ------RRSPTTVTSSVRSSSYHSPTRC------------NS 436
            :..:.   .|....:.::||.|.      .........:|....:..|.:|            |.
  Fly   464 VNAQHLSAHAGGGVNGANTRRHTVGPGDVAHEQALANPNVPPIDFKCPPQCSDPTQPVPYYPVNL 528

  Fly   437 PMSSAQQQANAISRPS---SPAAGTRHSTYGDRDRSGH---HSSVSRT-----PSHSSQKSIEG- 489
            ||...|...|...:..   .|......|::|.|...|.   |.....|     |:...|....|
  Fly   529 PMLQNQPLHNLTIKDQHLLKPPVVMGASSFGRRASDGGANLHIYYPATGTVVGPAQGQQMDTAGY 593

  Fly   490 --------DVVVVRE--PRIERR-------------------DSLRQERGGGSPRDRG---DCGI 522
                    |.:.|:|  |..|:.                   .|..|:|||......|   |..:
  Fly   594 YINPNCGTDPLAVQELSPLNEQSVAQMQCCQENATGECNEELQSYMQKRGGTQRHTVGCTEDLSV 658

  Fly   523 PPGSPGGNSSGSTSASPSVHHR-------ANSGPTIAISMFHDPDSN-------------SVVNP 567
            ..||..|:.|.:.:.|.::..|       ....|.|...:..:.:|.             |...|
  Fly   659 AHGSGAGSQSQAPTTSSNMRQRRTGLLTVTERPPVIPPEIIREVESRMKRDYLPPTLKSLSQSPP 723

  Fly   568 NGS-------PMMNNSSPGMPGS---------------PCNTPGGQLWKTRLTNI---------- 600
            ||:       ||..:.....|.|               |.|....::..::|..:
  Fly   724 NGTYPVGAALPMGMSKGLSPPHSLPLVAAAGGSVPLVAPNNRRIHRVVHSKLPTVQEGATIGRYS 788

  Fly   601 ---------KNSFLG---------------------SPRFHRRKMQVSADEVHLTP--------- 626
                     |:.|.|                     ||......:.:....:|..|
  Fly   789 PVRRASEGSKSQFQGPLQECQSLQKGIAQRNFLVAPSPPLLENSISLPGSPIHGKPGMGLQLALR 853

  Fly   627 -----ESSPELTKRSWFGNLITT----EKDETFTILVKGKPIATVKAHLI------------HAF 670
                 |..||..|     ||:..    .|::..:..:..|.|:|   |::            ||.
  Fly   854 RGHDIEVPPEAIK-----NLMPALDRLVKEQRVSFEIANKIIST---HVVPMDLAPLLGLAAHAS 910

  Fly   671 LSMA------ELSHSV---------------VSPTSFRVEYKRNGNGPVMFQRHVKFQVDISAIC 714
            .:.|      :.||..               |||.|.      ...|.|........|:....||
  Fly   911 SAAAVSGGHLDQSHFTHLQQQQQQQHMLSFSVSPLSM------PQGGAVNASLTSAKQMFGQPIC 969

  Fly   715 KQGDIADMLFALTFTLLSGNIRRFRRI------------CEHIQSQVCSKRFPGPSSP------- 760
            .......|..||........:.:|..|            |   ||.|.|..|.|..||
  Fly   970 GYTQYQPMTLALQPQHQQQLVGQFSSINLGASNSNSSSGC---QSPVFSTSFSGSCSPNPYLPGA 1031

  Fly   761 -----------------------PTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDME------ 796
                                   .::|..|.|.||.::..:.:::.|.....|....|:
  Fly  1032 AGGSSPLHQITKGISGLSTGCAGGSITRGTSAASEGAAAAAAANQPLDLSMDVCGGVMDQQPTDY 1096

  Fly   797 ------------------------------------NDSIFSYKSGNGRRASTTN--------NN 817
                                                |..|...::|||:...|.:        ..
  Fly  1097 AATNWFMPTASYYDMKPLNLSPAQPVRVVPTPPASPNLCIIQEENGNGQMCHTISTGTPYAGCTG 1161

  Fly   818 NANP----VDIPGSPIAVRSNSETAEHERNRELQSERQATTMS 856
            ...|    .|:.||.|.:.:.|  :::.|:.|...|:....||
  Fly  1162 GITPQICLTDVQGSEITLVALS--SDNSRDSEDSLEQHTPVMS 1202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	123/252 (49%)
		S_TKc	18..269	CDD:214567	122/250 (49%)
		UBA_BRSK	298..350	CDD:270525	8/55 (15%)
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	122/251 (49%)
		S_TKc	41..292	CDD:214567	122/250 (49%)
		UBA_SIK	335..380	CDD:270523	12/62 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010