DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sff and CG4629

DIOPT Version :9

Sequence 1:	NP_648814.3	Gene:	sff / 39732	FlyBaseID:	FBgn0036544	Length:	861	Species:	Drosophila melanogaster
Sequence 2:	NP_608564.3	Gene:	CG4629 / 33284	FlyBaseID:	FBgn0031299	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	132/551 - (23%)
Similarity:	234/551 - (42%)	Gaps:	114/551 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKII--NREKLSESVLMKVEREIAIMKLIDHPHV 77
            :|.||....:|:|....|||.||.:...|||||::  :|..|....|..:..|||.::.:.||::
  Fly    63 IGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNI 127

  Fly    78 LGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLK 142
            |.|.:|.|....:||:.|.:.||||::::.:.|.|....|....:|::.|:...||....|||:|
  Fly   128 LRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIK 192

  Fly   143 PENLLLDEKNNIKIADFGMAS--LQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL 205
            .||:||..::.:|:||||.::  :..|...|:|.||||.||.||:...:.|.|...|||:.|::|
  Fly   193 AENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILL 257

  Fly   206 YALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVT 270
            |.::||.:||....:..|...:.:|.:.:|..:...|..|::.::...|.:|.|:.::....:||
  Fly   258 YFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVT 322

  Fly   271 AGGKGELELELPMMEVVQTHVIPTATAV--------------------DPDVLNAICSLGCFKEK 315
            .   .:|..:|...|:.| |..|...::                    ...|.....|:...::.
  Fly   323 C---PKLSADLMQWEINQ-HTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQD 383

  Fly   316 EKLIQELL------------------------SSSHNTEKVIYFLLLERKRRRPALEDDDEIAQK 356
            |..:|..|                        .:...|.:.::...|::|......|.:.::|..
  Fly   384 EMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFCGSLKKKVTPMETEPEKQLANG 448

  Fly   357 SRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRRQAFNFRSYSSTRNHQRRSPTTVTS 421
            .:|           :.:.:||..|.    :::|..||        |::|.:........||.
  Fly   449 GQS-----------IGSAKINPWNV----EVAEDCPL--------FKNYDAETGSCVMLPTN--- 487

  Fly   422 SVRSSSYHSPTRCNSPMSSAQQQANAI-------------SRPSSPAAGTRHSTYGDRDRSGHHS 473
                      |...|.:.:.:.:|..|             :|.|.|    |....|     .:..
  Fly   488 ----------TEDLSQLGALEFEARQILAELGLTSEMLINARQSGP----RSDIIG-----AYRI 533

  Fly   474 SVSRTPSHS--SQKSIEGDVVVVREPRIERR 502
            .|:|....|  ::|.:|  :.:..||::|:|
  Fly   534 VVNRLQKQSWLARKHVE--MALHSEPKVEKR 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	85/256 (33%)
		S_TKc	18..269	CDD:214567	84/254 (33%)
		UBA_BRSK	298..350	CDD:270525	9/95 (9%)
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	85/257 (33%)
CG4629	NP_608564.3	S_TKc	66..321	CDD:214567	84/254 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940