Protein Alignment sff and Sik2

DIOPT Version :9

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_569972.1
• Gene: Sik2 / 31170
• FlyBaseID: FBgn0025625
• Length: 1398
• Species: Drosophila melanogaster
• Alignment Length: 981
• Identity: 270/981 - (27%)
• Similarity: 398/981 - (40%)
• Gaps: 269/981 - (27%)

  Fly    15 VGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLIDHPHVLG 79
            ||.|.:|:|:|||...:|||..|.:...:||||||::.:|.::.|.||.||:.|||.:.|||::.
  Fly   138 VGFYDIERTIGKGNFAVVKLARHRITKNEVAIKIIDKSQLDQTNLQKVYREVEIMKRLKHPHIIK 202

  Fly    80 LSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPE 144
            |..|.|.|..:|::.|:.|.||:|||:.|.||::...||..|.|||||:::||...|.|||||.|
  Fly   203 LYQVMETKNMIYIVSEYASQGEIFDYIAKYGRMSESAARFKFWQIISAVEYCHKKGIVHRDLKAE 267

  Fly   145 NLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALL 209
            |||||...||||||||.::....|.:|.|.||||.||.|||..|::|.|.:.|:||.||:||.|:
  Fly   268 NLLLDLNMNIKIADFGFSNHFKPGELLATWCGSPPYAAPEVFEGKQYTGPEIDIWSLGVVLYVLV 332

  Fly   210 VGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGK 274
            .||||||...|:.|.::|..|.|.||.|:..:|:.|:|.|:.:.|.||.|:.:|.||.|
  Fly   333 CGALPFDGSTLQSLRDRVLSGRFRIPFFMSSECEHLIRRMLVLEPTRRYTIDQIKRHRW------ 391

  Fly   275 GELELELPMMEVVQTHVI--------PTATAVDP--DVLNAICS-LGCFKEKEKLIQELLSSSHN 328
                    |...:..||:        ...|:|:|  |:|..:.. :|...:|.:  ..|..::::
  Fly   392 --------MCPELLEHVLIAKYNLGAERQTSVEPSEDILRIMAEYVGIGSDKTR--ASLKKNTYD 446

  Fly   329 TEKVIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPL 393
            ....||.||            .|.::.|....                ||..|.:....:..|.:
  Fly   447 HVAAIYLLL------------QDRVSHKKEQS----------------NGLGASALASSTSASRM 483

  Fly   394 TPRRQAFNFRSYSSTRNH-------QRRSPTTVTSSVRSSSYHSPTRCNSPMS------SAQQQA 445
            .          |||..:|       |::|.|..|||:.:..     :|:..:|      .:::.|
  Fly   484 I----------YSSRNDHQPTQQQSQQQSKTISTSSILAKD-----QCHKRLSRHQTVLMSERNA 533

  Fly   446 NAISRPSSPAAGT-RHSTYGDRD----RSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSL 505
            :|.:.|:.|..|. .::.||...    .:||        ||     :.|.:
  Fly   534 HAGATPTVPDPGPGYYAKYGPLQLPLPLTGH--------SH-----LTGYL-------------- 571

  Fly   506 RQERGGGSPRDRGDCGIP----------PGSPGGNSSGSTSASPSVHHRANSGP----TIAISMF 556
               .|||...|..  |||          ..||..::..|||:....|..::|.|    .:|||:.
  Fly   572 ---NGGGVEVDAS--GIPLPMRYTPLPTAASPAPSNCSSTSSRVGRHSLSSSSPRSHRPVAISLS 631

  Fly   557 HDPDSNSVVNPNGSPMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFL--GSPRFHRRKMQVSA 619
            .| ::.|:.|.....||...     |.|....|..|...:|....:.|:  .|....|..:|.|.
  Fly   632 ID-NNPSLANLRCREMMEAG-----GGPVGAVGVPLASKQLHQTISEFIIKQSTEDCRALLQQST 690

  Fly   620 ------DE--------------VHLTPESS---PELTKRSWFGNLITTEKDETFTILVKGKPIAT 661
                  |:              ...||.||   ||.......|.             :.||.|.|
  Fly   691 AVAEGKDDPPKAESSVGGVPPPASTTPTSSTAGPESGSAPCPGE-------------INGKTIKT 742

  Fly   662 VKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGNGPVMFQ----------RHVKFQVDISAICKQ 716
            :.:.  .:|.|.|.|..      |||  ||.:.....:||          :..|.:|.:.:  ..
  Fly   743 MSSS--SSFDSKANLGQ------SFR--YKMSAEASKLFQTLQESPLPVEQRTKRRVHVGS--TN 795

  Fly   717 GDIADMLFALTFTLLSGNIRRFRRI-----------CEHIQSQVCSKRFPGPSSP---------- 760
            |...|..........:|:.|..:::           ||..|.     ..||.:|.
  Fly   796 GSGGDSGQETNDAKSNGDSRSEKKVLAQGSSSTDEGCETDQG-----NDPGSASQESKGSNGGGS 855

  Fly   761 ------PTVTS---VTQAV---------------SESSSCGSVSSERLSYKRQVIEN-----DME 796
                  ||..|   :|:.|               |.|||.|.::....||.:.:.:|     ...
  Fly   856 GNANGGPTSHSSSDLTRLVGTTTSGQSHKMRSYASSSSSSGVLAGSAGSYSKSLSQNLSRGSSKS 920

  Fly   797 N-----DSI-FSYKSGNGRRASTTNNNN--ANPVDIPGSPIAVRSNSETAEHERNRELQ-SERQA 852
            |     ||: |:..||.|...|...:::  |.|.....||..:.|     ||...|.|. |....
  Fly   921 NCSGPYDSLDFALPSGKGSLPSCMGSSSMLATPTPASASPAGISS-----EHSSERSLYGSHNSC 980

  Fly   853 TTMSGS 858
            ..|.|:
  Fly   981 IHMPGA 986

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	122/252 (48%)
		S_TKc	18..269	CDD:214567	121/250 (48%)
		UBA_BRSK	298..350	CDD:270525	11/54 (20%)
Sik2	NP_569972.1	STKc_SIK	140..392	CDD:270973	122/265 (46%)
		S_TKc	141..392	CDD:214567	122/264 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940