Protein Alignment sff and Nuak1

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001100244.1
• Gene: Nuak1 / 299694
• RGDID: 1309956
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 179/563 - (31%)
• Similarity: 266/563 - (47%)
• Gaps: 86/563 - (15%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESV-LMKVEREIAIMKLIDHPHVLGLS 81
            |.|::|||||..|.||.......|:.||||.|.::|:.:.: ::.:.|||.||..::|||::.:.
  Rat    56 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIY 120

  Fly    82 DVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 146
            :|:|||..:.:|:|:.|.|||:||:.::.||:.:|.|.|||||:||:.:||.:.:.|||||.||:
  Rat   121 EVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI 185

  Fly   147 LLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            |||:..||||||||:::|......|:|.||||.||.||::.|..|.|.:.|.|:.||:||.|:.|
  Rat   186 LLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLIYG 250

  Fly   212 ALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVTAGGKGE 276
            .:|||..:.:.|:.::..|.:..| ..|.|.:.|:|.|:.||||||.|:.:|..|.||..|.|..
  Rat   251 TMPFDGFDHKNLIRQISSGEYREP-TQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSS 314

  Fly   277 L-------ELELPMM-EVVQTHVIPTATAVDPD------------VLNAICSLGCFKEKEKLI-- 319
            :       :.|.|:: .::..|...|....:.|            ||....||...|::....
  Rat   315 VCDCDALPDSESPLLARIIDWHHRSTGLQAEADAKMKAKPGASEVVLERQRSLKKSKKENDFPQS 379

  Fly   320 -QELLSSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSE--LDAV------DPPRKRLDTCR 375
             |:.|..|.:.        |..||.:..|:.......:|.|.  ::.:      .|.:...|.||
  Rat   380 GQDSLPESPSK--------LSSKRPKGILKKRSNSEHRSHSTGFIEGIVGPALPSPFKMEQDLCR 436

  Fly   376 INGTNAPSYGQISEGSPLTPRRQAFNFR-SYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMS 439
               |..|        .|.:|..|..:.: |...:....::.....|....|..|.||.|..|  |
  Rat   437 ---TAIP--------LPGSPEAQGSSGKLSLKQSATMPKKGILKKTQQRESGYYSSPERSES--S 488

  Fly   440 SAQQQANAI------SRPSSPAAGTRHSTYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPR 498
            ......|.|      |.|..||.||.||....|.....||  ||....::..::.|       |.
  Rat   489 ELLDSNNVIISSGLSSPPPDPARGTSHSLSCRRKGILKHS--SRYSDGATDPALTG-------PE 544

  Fly   499 IERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGSTSASPSV 541
            |...:||.                |||.|....|.|.|...|:
  Rat   545 IPTLESLS----------------PPGVPSDGISRSYSRPSSI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	110/251 (44%)
		UBA_BRSK	298..350	CDD:270525	13/66 (20%)
Nuak1	NP_001100244.1	STKc_NUAK	54..307	CDD:270975	110/251 (44%)