Protein Alignment sff and Brsk2

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: XP_038957200.1
• Gene: Brsk2 / 293631
• RGDID: 1566256
• Length: 757
• Species: Rattus norvegicus
• Alignment Length: 819
• Identity: 434/819 - (52%)
• Similarity: 526/819 - (64%)
• Gaps: 128/819 - (15%)

  Fly     9 AENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLID 73
            |::.|:|||||||||||||||||||||:|||..:||||||:|||||||||||||||||||:|||:
  Rat    11 AQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 75

  Fly    74 HPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICH 138
            |||||.|.|||||||||||:|||||||||||||||||||||||||||||||||||||||||||||
  Rat    76 HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICH 140

  Fly   139 RDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGV 203
            ||||||||||||:|||:||||||||||...|:|||||||||||||||||||||||||||||||||
  Rat   141 RDLKPENLLLDERNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGV 205

  Fly   204 ILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPW 268
            ||:|||||||||||||||||||||||||||:|||:||||||||||||||:..|||||..|.:|.|
  Rat   206 ILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIW 270

  Fly   269 VTAGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVI 333
            . .|||.|.|.|.|:...||...:|:...:|||||:::.|||||:::.||:|:|||...|.||:|
  Rat   271 Y-IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMI 334

  Fly   334 YFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRRQ 398
            |||||:||.|.|:.||:|   ...|:|   :||||||:|                  ||:..|
  Rat   335 YFLLLDRKERYPSHEDED---LPPRNE---IDPPRKRVD------------------SPMLNR-- 373

  Fly   399 AFNFRSYSSTRNHQRRSPTTVTSSVRS-SSYHSPTRCNSPMSSAQQ-QANAISRPSSPAAGTRHS 461
                        |.:|.|...:..|.| :...||......:..||. |:.|:...|...| ..|.
  Rat   374 ------------HGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQSKAVFSKSLDIA-EAHP 425

  Fly   462 TYGDRDR----SGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGI 522
            .:...||    ||..|.:|.:|..|              ||:....|.|     |||     ...
  Rat   426 QFSKEDRSRSISGASSGLSTSPLSS--------------PRVTPHPSPR-----GSP-----LPT 466

  Fly   523 PPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPCNT 587
            |.|:|                            .|.|..:....||.:|         |.||  :
  Rat   467 PKGTP----------------------------VHTPKESPAGTPNPTP---------PSSP--S 492

  Fly   588 PGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADE--VHLTPESSPELTKRSWFGNLITTEKDETF 650
            .||..|:|||.:|||||||||||||||:||...|  .:|||||||||.|:|||||.|..||:|..
  Rat   493 VGGVPWRTRLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFINLEKEEQI 557

  Fly   651 TILVKGKPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGNGPVMFQRHVKFQVDISAICK 715
            .:::|.||::::||.::|||||:..|||||:|.||||.|||..| ||.:||:.|||||||:  ..
  Rat   558 FVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG-GPAVFQKPVKFQVDIT--YT 619

  Fly   716 QGDIADM---LFALTFTLLSGNIRRFRRICEHIQSQVCSKRFPGPSSPPTVTSVTQAVSESSSCG 777
            :|..|..   ::::|||||||..|||:|:.|.||:|:.|.. ..||:        |.:|::::|.
  Rat   620 EGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTH-DQPSA--------QHLSDTTNCM 675

  Fly   778 SVSSERLSYKRQVIEN--DMENDSIFSYKSGNGRRASTT 814
            .|.:.|||.....:.|  |:........|:|...:|.:|
  Rat   676 EVMTGRLSKCGTPLSNFFDVIKQLFSDEKNGQAAQAPST 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	225/252 (89%)
		UBA_BRSK	298..350	CDD:270525	30/51 (59%)
Brsk2	XP_038957200.1	STKc_BRSK1_2	18..271	CDD:270983	225/252 (89%)
		UBA_BRSK	298..351	CDD:270525	30/52 (58%)