Protein Alignment sff and TSSK2

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_443732.3
• Gene: TSSK2 / 23617
• HGNCID: 11401
• Length: 358
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 99/300 - (33%)
• Similarity: 163/300 - (54%)
• Gaps: 31/300 - (10%)

  Fly    24 LGKGQTGLVKLGVHCVIGKKVAIKIINREKL-SESVLMKVEREIAIMKLIDHPHVLGLSDVYENK 87
            ||||....||......:...||:|||:|:|. ::.|...:.||:.|:..::|..::...:::|..
Human    18 LGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETS 82

  Fly    88 K-YLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEK 151
            . .:|:|:|....|:|.:::..:|.|....|||.|||:.||:.:||...|.|||||.||||||:.
Human    83 DGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKD 147

  Fly   152 NNIKIADFGMAS--LQPAGSML---ETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVG 211
            .|||::|||.:.  |:.:...:   :|.|||..||.|||::...|..:..|:||.|||||.::.|
Human   148 FNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCG 212

  Fly   212 ALPFDDDNLRQLL--EKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV----- 269
            ::|:||.::|::|  :|..|..|.....:..:|:.|:..|::.:..:||.:.||..|.|:
Human   213 SMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKP 277

  Fly   270 --TAG------GKGELELELPMMEVVQTHVIPTATAVDPD 301
              |:.      |:|:...|..         :.|.|.:.||
Human   278 KATSSASFKREGEGKYRAECK---------LDTKTGLRPD 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	90/253 (36%)
		UBA_BRSK	298..350	CDD:270525	1/3 (33%)
TSSK2	NP_443732.3	STKc_TSSK1_2-like	10..272	CDD:271067	90/253 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	302..358		2/6 (33%)