Protein Alignment sff and PASK

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_001239048.1
• Gene: PASK / 23178
• HGNCID: 17270
• Length: 1330
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 91/267 - (34%)
• Similarity: 140/267 - (52%)
• Gaps: 20/267 - (7%)

  Fly    18 YRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESV------LMKVEREIAIMKLIDHPH 76
            |.....||.|..|.|...|.....|:|.:|.|.:||:.|..      |.||..||||:..::|.:
Human   999 YSTMSPLGSGAFGFVWTAVDKEKNKEVVVKFIKKEKVLEDCWIEDPKLGKVTLEIAILSRVEHAN 1063

  Fly    77 VLGLSDVYENKKYLYLILE-HVSGGELFDYLVKKGRLTPKEARKFFRQI-------ISALDFCHS 133
            ::.:.|::||:.:..|::| |.||.:||.::.:..||....|...|||:       :||:.:...
Human  1064 IIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQVRAGQSRLVSAVGYLRL 1128

  Fly   134 HSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADV 198
            ..|.|||:|.||:::.|...||:.|||.|:....|.:..|.||:..|..|||:.|..|.|.:.::
Human  1129 KDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGKLFYTFCGTIEYCAPEVLMGNPYRGPELEM 1193

  Fly   199 WSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEI 263
            ||.||.||.|:....||.:      ||:......|.|:.|..:..||:.|:::..|:||.||.::
Human  1194 WSLGVTLYTLVFEENPFCE------LEETVEAAIHPPYLVSKELMSLVSGLLQPVPERRTTLEKL 1252

  Fly   264 NRHPWVT 270
            ...||||
Human  1253 VTDPWVT 1259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	88/264 (33%)
		UBA_BRSK	298..350	CDD:270525
PASK	NP_001239048.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..47
		PAS	133..232	CDD:238075
		PAS	344..401	CDD:214512
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	837..857
		STKc_PASK	998..1258	CDD:270906	88/264 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1305..1330