Protein Alignment sff and Snrk

DIOPT Version :10

• Sequence 1: NP_648814.3
• Gene: sff / 39732
• FlyBaseID: FBgn0036544
• Length: 861
• Species: Drosophila melanogaster
• Sequence 2: NP_598502.2
• Gene: Snrk / 20623
• MGIID: 108104
• Length: 748
• Species: Mus musculus
• Alignment Length: 742
• Identity: 192/742 - (25%)
• Similarity: 305/742 - (41%)
• Gaps: 181/742 - (24%)

  Fly    13 QFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVEREIAIMKLIDHPHV 77
            :..|.|.|:||||:|...:|||..|...|:|||:|:|::.||.......:.:|:..|||:.||::
Mouse    11 KIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHPNI 75

  Fly    78 LGLSDVYENKKYLYLILEHVSGGELFDYLVK-KGRLTPKEARKFFRQIISALDFCHSHSICHRDL 141
            :.|.:|.:.:..||||||...||::|||::| :..|....|:|:|.||:.|:.:||...:.||||
Mouse    76 VRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDL 140

  Fly   142 KPENLLLDEKNN-IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVIL 205
            ||||::..||.. :|:.|||.::....|..|.|||||..|:.||::.|::||....|:||.||||
Mouse   141 KPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVIL 205

  Fly   206 YALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVT 270
            :.|:.|..||.:.|..:.|..:....:.:|..|...|:.|:..|::.:|.||.:|.||..|||:.
Mouse   206 FMLVCGQPPFQEANDSETLTMIMDCKYTVPPRVSAGCRDLITRMLQRDPKRRASLEEIESHPWLQ 270

  Fly   271 -AGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICS---LGCFKEKEKLIQELLSSSHNTEK 331
             .......:..:|::....         :..:..|:|..   ||...:::.:::.|.::.:|...
Mouse   271 GVDPSPATKYNIPLVSYKN---------LSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHIT 326

  Fly   332 VIYFLLLERKRRRPALEDDDEIAQKSRSELD-----------AVDPPRKRLDTCRINGTNAP-SY 384
            ..||||.||..|.   :.:.||..:|.|..:           .:|.|:...|..    |..| |:
Mouse   327 ATYFLLAERILRE---KQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQDLEDDL----TATPLSH 384

  Fly   385 GQISEGSPLTPRRQAFNFRSYSSTRNHQRRS------------------PTTVTSSVRSSSYHSP 431
            ..:    |.:|.|...|.     ...|:.:.                  .|...:|::.::  |.
Mouse   385 ATV----PQSPARAGDNV-----LNGHRSKGLCDPAKKDELPELAGPALSTVPPASMKPAA--SG 438

  Fly   432 TRC--------------NSPMSSAQQQA---------NAISRPSSP------------------- 454
            .:|              ..|:|.:.|..         ...||.|:|
Mouse   439 RKCLFRVEEDEEEDEEDKKPVSLSTQVVLRRKPSVTNRLTSRKSAPVLNQIFEEGESDDEFDMDE 503

  Fly   455 --------------AAGTRHSTYGDRDRSGHHSSVSRTPS----HSSQKSIEGDVVVVREPRIER 501
                          :.||.|..|..|...|..||.|.:.:    ..|::.::.|......  ..|
Mouse   504 NLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSDDDSESRRRLDKDSGFAYS--WHR 566

  Fly   502 RDS--------------LRQERGGG----SPRDRGDCGIPPGSPGGNSSG------------STS 536
            |||              .:...|||    ||.::|..|...|..||..||            |:|
Mouse   567 RDSSEGPPGSEGDGGGQSKPSSGGGVDKASPGEQGTGGGSQGGSGGTPSGTAGSSRRCAGPDSSS 631

  Fly   537 ASPSVHHRANSGPTIAISM----------FH------DPD----SNSVVNPNGSPMMNNSSPGMP 581
            .||:....|..|..:..|:          .|      ||.    |:..|....:..|..|:||
Mouse   632 PSPASASAAPRGAELVQSLKLVSLCLGSQLHGAKYILDPQKALFSSVKVQEKSTWKMCISAPG-- 694

  Fly   582 GSPCNTPGGQLWKTRLTNIKNSFLGSP 608
                .:|...|...|...::|:.|..|
Mouse   695 ----PSPSADLDPVRTKKLRNNALQLP 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sff	NP_648814.3	STKc_BRSK1_2	16..269	CDD:270983	102/254 (40%)
		UBA_BRSK	298..350	CDD:270525	13/54 (24%)
Snrk	NP_598502.2	STKc_SNRK	12..269	CDD:270976	102/256 (40%)
		UBA_SNRK	288..335	CDD:270524	10/55 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..415		6/40 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	491..640		31/150 (21%)